IP Library Granted Patent US 10,010,671
Granted Patent B2
US 10,010,671 · App. 14/456,416 · Granted Jul 3, 2018

Drug delivery device

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Quick Facts
Patent No.
US 10,010,671
App. No.
14/456,416
Granted
Jul 3, 2018
Kind
B2
Abstract

Embodiments include a displacement-generating battery cell for driving a drug-delivery device. The cell includes at least one volume-changing element. The cell also includes a housing formed according to a concertina-shaped design with folds in the walls thereof and containing an internal chemical reaction system. The arrangement of the chemical reaction system is such that as the cell is discharged, the volume-changing element expands, thereby lengthening the battery and thus reducing the extent of said folds, such that the cell becomes taller to reflect the expansion of the volume-changing component.

Claims (40)

1. A displacement-generating battery cell for driving a drug-delivery device and comprising at least one volume-changing element,

said cell comprising a housing formed according to a concertina-shaped design with folds in the walls thereof and containing an internal chemical reaction system,

said chemical reaction system comprising a first electrode and a second electrode,

the second electrode being said volume-changing element,

the arrangement of said chemical reaction system and said housing being such that:

an expansion of the volume-changing element in a direction lengthens the cell and thus reduces the extent of said folds,

the cell becomes taller in the direction to reflect the expansion of said volume-changing element, and

the expansion of the volume-changing element increases the surface area between the first electrode and the second electrode, and

the chemical reaction system being configured such that discharging of the cell results in the expansion of the volume-changing element in the direction.

2. A displacement-generating battery cell according to claim 1 , wherein the volume of the displacement-generating battery cell is changed as its respective electrical capacity is changed.

3. A displacement-generating battery cell according to claim 1 , wherein at least one component of the displacement-generating battery cell undergoes a volume change of at least 20%.

4. A displacement-generating battery cell according to claim 1 , wherein at least one component of the displacement-generating battery cell undergoes a volume change of at least 30%.

5. A displacement-generating battery cell according to claim 1 , wherein the displacement derived from the displacement-generating battery cell exerts a force of at least 1 kg/sq cm.

6. A displacement-generating battery cell according to claim 1 , wherein the displacement derived from the displacement-generating battery cell exerts a force of at least 10 kg/sq cm.

7. A displacement-generating battery cell according to claim 1 , the arrangement of said chemical reaction system and said housing further being such that a contraction of the volume-changing element in the direction shortens the battery and thus increases the extent of said folds, such that the cell becomes shorter in the direction to reflect the contraction of said volume-changing element, and

the chemical reaction system being configured such that charging the cell results in the contraction of the volume-changing element in the direction.

8. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell has a diameter of between 10 and 30 mm.

9. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell has a diameter of between 20 and 60 mm.

10. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an electrode, and the electrode comprises a pressed, pasted or sintered porous structure.

11. A displacement-generating battery cell according to claim 1 , where said chemical reaction system is chosen from the group consisting of Li—Sn, (Li)LiC 6 —Sn, Fe—LaNi 5 , lithium-lead, lithium-antimony, lithium-silicon and lithium bismuth.

12. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an electrode, and the electrode comprises tin, iron or lithium alloys.

13. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an electrode, and the electrode comprises lithium-aluminum, lithium-magnesium, lithium-aluminum-magnesium, lithium-lead, lithium-antimony, lithium-silicon or lithium-bismuth.

14. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an organic solvent or a polymer electrolyte together with a lithium ion-providing salt.

15. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an electrode, and the electrode expands over 250% in volume during discharge.

16. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises a tin cathode, a lithium anode and an electrolyte.

17. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises an electrolyte, and the electrolyte comprises a solvent of a mixture of ethylene carbonate and ethyl methyl carbonate with dissolved lithium hexafluorophosphate.

18. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises a porous, tin cathode.

19. A displacement-generating battery cell according to claim 1 , wherein the displacement-generating battery cell comprises a plurality of anodes and a plurality of cathodes.

20. A displacement-generating battery cell according to claim 1 , wherein said chemical reaction system is non-gassing.

21. A displacement-generating battery cell according to claim 1 , wherein:

said chemical reaction system is an electrochemical reaction system,

said chemical reaction system comprises an electrolyte,

the first electrode is an anode of the electrochemical reaction system,

the second electrode is a cathode of the electrochemical reaction system, and

the chemical reaction system is configured such that discharging of the cell results in the expansion of the volume-changing element by ions derived from the first electrode penetrating the second electrode.

22. A displacement-generating battery cell, the displacement-generating battery cell comprising:

a housing having a concertina-shaped design with folds in the walls thereof, the housing having a first end and a second end, a distance between the first and second ends of the housing defining a housing length; and

an electrochemical reaction system comprising an anode and an expandable cathode, the expandable cathode having a first end and a second end, a distance between the first and second ends of the expandable cathode defining a cathode length,

wherein the electrochemical reaction system is contained within the housing, and

wherein the first and second ends of the housing are coupled with the first and second ends of the expandable cathode, respectively, such that an expansion of the cathode that increases the cathode length causes a corresponding increase in the housing length and such that the expansion of the cathode increases the surface area between the anode and cathode.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2022
From: STEADYMED LTD.
To: UNITED THERAPEUTICS CORPORATION
Reel/Frame 060520/0015 →
CORRECTIVE ASSIGNMENT TO CORRECT THE DATE OF EXECUTION OF ASSIGNMENT DOCUMENT BY INVENTOR, AMIR GENOSAR PREVIOUSLY RECORDED ON REEL 033566 FRAME 0283. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNORS HAVE SOLD, ASSIGNED AND TRANSFERRED TO ASSIGNEES ALL RIGHT, TITLE AND INTEREST IN SAID INVENTION AND APPLICATION. Recorded Aug 25, 2014
From: GENOSAR, AMIR; AURBACH, DORON; MARKEVICH, ELENA; SALITRA, GRIGORY; GOLDSTEIN, JONOTHAN; LEVI, MIKHAIL; FLEISCHER, NILES; BACHAR, YEHUDA; ALDAR, YOSSI
To: STEADYMED LTD.
Reel/Frame 033609/0577 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2014
From: GENOSAR, AMIR; AURBACH, DORON; MARKEVICH, ELENA; SALITRA, GRIGORY; GOLDSTEIN, JONOTHAN; LEVI, MIKHAIL; FLEISCHER, NILES; BACHAR, YEHUDA; ALDAR, YOSSI
To: STEADYMED LTD.
Reel/Frame 033566/0283 →