Dissolvable on-command implant
The purpose of the “Dissolvable on-command Implant” is to act as a pressure equalizer tube in the eardrum, which has the unique characteristic that the tube can be dissolved with a specially formulated drop solution on-command. This tube can have various shapes and sizes, although the tube is usually a cylindrical tube with a hollow center, which maintains a ventilatory port for the middle ear space. With this design, the ear tube promotes drainage of middle ear fluid, lets air enter the middle ear, and allows for instillation of antibiotic drops.
1. A dissolvable on-command tympanostomy tube that is insertable into an eardrum of an ear of a patient, comprising:
a tube having two flared ends, wherein
the tube is comprised of a first material that is configured to be insoluble in bodily fluids of the patient but disintegrate upon intentional contact with a second material introduced from an extracorporeal environment into the ear of the patient, the disintegration being based on a chemical reaction between the first material and the second material,
the two flared ends include an inner flange and an outer flange, the inner flange and the outer flange being connected by a connecting member having a through-hole that extends from the inner flange through the connecting member to the outer flange, and
the inner flange is made of a third material that is biodegradable.
2. The dissolvable on-command tympanostomy tube of claim 1 , wherein the inner flange has a larger diameter than the outer flange.
3. The dissolvable on-command tympanostomy tube of claim 1 , wherein the inner flange is tailed.
4. The dissolvable on-command tympanostomy tube of claim 1 , wherein
an inner portion including the inner flange and a portion of the connecting member adjacent to the inner flange are made of the first material, and
an outer portion including the outer flange and a remaining portion of the connecting member are made of a third material, the third material being biodegradable.
5. The dissolvable on-command tympanostomy tube of claim 1 , wherein
at least one of the inner flange and the outer flange are made of the first material and the connecting member is made of a fourth material, the fourth material being configured to disintegrate when in contact with the second material according to a chemical reaction between the fourth material and the second material, and
the first material degrades faster than the fourth material when both the first material and the fourth material are in contact with the second material.
6. The dissolvable on-command tympanostomy tube of claim 1 , wherein a portion of the connecting member that is adjacent to the outer flange has a greater thickness than a thickness of a portion of the connecting member that is adjacent to the inner flange.
7. The dissolvable on-command tympanostomy tube of claim 1 , wherein an inner portion including the inner flange and a portion of the connecting member adjacent to the inner flange contains a plurality of micro-cavities.
8. The dissolvable on-command tympanostomy tube of claim 1 , wherein a portion of the connecting member adjacent to the inner flange contains a plurality of micro-cavities.
9. The dissolvable on-command tympanostomy tube of claim 1 , wherein the inner flange has a coating made of the first material.
10. The dissolvable on-command tympanostomy tube of claim 1 , wherein an outer portion including the outer flange and a portion of the connecting member adjacent to the outer flange is coated with a nitrocellulose coating.
11. The dissolvable on-command tympanostomy tube of claim 1 , wherein the first material is a mixture of methyl methacrylate, butyl methacrylate and 2-(Dimethylamino) ethyl methacrylate.
12. The dissolvable on-command tympanostomy tube of claim 1 , wherein the second material is a liquid with a pH between 2.89 and 5.
13. The dissolvable on-command tympanostomy tube of claim 1 , wherein an inner portion of the tube degrades more rapidly than an outer portion of the tube upon the contact with the second material.
14. The dissolvable on-command tympanostomy tube of claim 1 , wherein the second material is ethanol.