IP Library Granted Patent US 9,233,932
Granted Patent B2
US 9,233,932 · App. 14/477,606 · Granted Jan 12, 2016

Oligomer-nitroimidazole anti-infective conjugates

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Quick Facts
Patent No.
US 9,233,932
App. No.
14/477,606
Granted
Jan 12, 2016
Kind
B2
Abstract

The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.

Claims (9)

1. A method for treating Giardia intestinalis infection in a patient in need thereof, the method comprising administering a therapeutically effective amount of a compound having the following structure:

wherein:

(a) is 2 or 3;

each instance of R 1 is hydrogen;

each instance of R 2 is hydrogen;

R 3 is selected from the group consisting of hydrogen, methyl and ethyl; and

(n) is an integer of from 3 to 7 inclusive.

2. The method of claim 1 , wherein (a) is 2 and R 3 is selected from the group consisting of methyl and ethyl.

3. The method of claim 1 , wherein (a) is 2 and R 3 methyl.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 34378, FRAME 0972 Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036855/0558 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
SECURITY INTEREST Recorded Dec 4, 2014
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 034378/0972 →