Granted Patent
B2
US 9,233,932 · App. 14/477,606 · Granted Jan 12, 2016
Oligomer-nitroimidazole anti-infective conjugates
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Abstract
The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
Claims (9)
1. A method for treating Giardia intestinalis infection in a patient in need thereof, the method comprising administering a therapeutically effective amount of a compound having the following structure:
wherein:
(a) is 2 or 3;
each instance of R 1 is hydrogen;
each instance of R 2 is hydrogen;
R 3 is selected from the group consisting of hydrogen, methyl and ethyl; and
(n) is an integer of from 3 to 7 inclusive.
2. The method of claim 1 , wherein (a) is 2 and R 3 is selected from the group consisting of methyl and ethyl.
3. The method of claim 1 , wherein (a) is 2 and R 3 methyl.
Assignments (4)
RELEASE OF SECURITY INTEREST
Recorded Apr 17, 2020
From: TC LENDING, LLC, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 053180/0009 →
RELEASE OF SECURITY INTEREST RECORDED AT REEL 34378, FRAME 0972
Recorded Oct 14, 2015
From: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
To: NEKTAR THERAPEUTICS
Reel/Frame 036855/0558 →
GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS
Recorded Oct 6, 2015
From: NEKTAR THERAPEUTICS
To: TC LENDING, LLC, AS COLLATERAL AGENT
Reel/Frame 036796/0562 →
SECURITY INTEREST
Recorded Dec 4, 2014
From: NEKTAR THERAPEUTICS
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 034378/0972 →