IP Library Granted Patent US 10,561,600
Granted Patent B2
US 10,561,600 · App. 14/492,344 · Granted Feb 18, 2020

Cosmetic active ingredient for combating the loss of volume of tissues, in particular of the face

Inventor: Jean Paufique (Objat, FR)
Assignee: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
A61K8/97A61K8/60A61Q19/08
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Quick Facts
Patent No.
US 10,561,600
App. No.
14/492,344
Granted
Feb 18, 2020
Kind
B2
Abstract

A cosmetic active ingredient obtained from roots of Paeonia albiflora , which is a hydrolyzate of roots of Paeonia albiflora including at least 30% of carbohydrates by weight relative to the total weight of dry materials. The cosmetic active ingredient can be used in a composition and in a cosmetic care process for care of the human skin.

Claims (44)

1. A method of providing a plumping-up effect to skin, comprising topically applying to skin of a subject in need thereof a cosmetic composition comprising an effective amount of a cosmetic active ingredient comprising an enzymatic hydrolyzate of roots of Paeonia albiflora with at least 30% of carbohydrates by weight relative to the total weight of dry materials of active ingredient,

wherein the 30% of carbohydrates comprises at least 80% oligosaccharides,

wherein the oligosaccharides are at least in part oligosaccharides of sucrose and glucose,

wherein there is more sucrose than glucose,

wherein the active ingredient is obtained by at least the following process:

solubilization of powder from Paeonia albiflora roots in water;

enzymatic hydrolysis;

separation of soluble and insoluble phases; and

enzymatic deactivation by heat treatment.

2. The method of providing a plumping-up effect to skin according to claim 1 , wherein the cosmetic composition is topically applied at least once daily.

3. The method of providing a plumping-up effect to skin according to claim 1 , wherein the cosmetic active ingredient is between 0.1 and 10% by total weight of the cosmetic composition.

4. A method for increasing thickness and volume of adipose tissue, comprising topically applying to skin of a subject in need thereof a cosmetic composition comprising an effective amount of a cosmetic active ingredient comprising an enzymatic hydrolyzate of roots of Paeonia albiflora with at least 30% of carbohydrates by weight relative to the total weight of dry materials of active ingredient,

wherein the 30% of carbohydrates comprises at least 80% oligosaccharides,

wherein the oligosaccharides are at least in part oligosaccharides of sucrose and glucose,

wherein there is more sucrose than glucose,

wherein the active ingredient is obtained by at least the following process:

solubilization of powder from Paeonia albiflora roots in water;

enzymatic hydrolysis;

separation of soluble and insoluble phases; and

enzymatic deactivation by heat treatment.

5. The method for increasing thickness and volume of adipose tissue according to claim 4 , wherein the cosmetic composition is topically applied at least once daily.

6. The method for increasing thickness and volume of adipose tissue according to claim 4 , wherein the cosmetic active ingredient is between 0.1 and 10% by total weight of the cosmetic composition.

7. A method for controlling communication between dermis and hypodermis, comprising topically applying to skin of a subject in need thereof a cosmetic composition comprising an effective amount of a cosmetic active ingredient comprising an enzymatic hydrolyzate of roots of Paeonia albiflora with at least 30% of carbohydrates by weight relative to the total weight of dry materials of active ingredient,

wherein the 30% of carbohydrates comprises at least 80% oligosaccharides,

wherein the oligosaccharides are at least in part oligosaccharides of sucrose and glucose,

wherein there is more sucrose than glucose,

wherein the active ingredient is obtained by at least the following process:

solubilization of powder from Paeonia albiflora roots in water;

enzymatic hydrolysis;

separation of soluble and insoluble phases; and

enzymatic deactivation by heat treatment.

8. The method for controlling communication between dermis and hypodermis according to claim 7 , wherein the cosmetic composition is topically applied at least once daily.

9. The method for controlling communication between dermis and hypodermis according to claim 7 , wherein the cosmetic active ingredient is between 0.1 and 10% by total weight of the cosmetic composition.

10. A method for filling in loss of structure and correcting for loosening of skin, comprising topically applying to skin of a subject in need thereof a cosmetic composition comprising an effective amount of a cosmetic active ingredient comprising an enzymatic hydrolyzate of roots of Paeonia albiflora with at least 30% of carbohydrates by weight relative to the total weight of dry materials of active ingredient,

wherein the 30% of carbohydrates comprises at least 80% oligosaccharides,

wherein the oligosaccharides are at least in part oligosaccharides of sucrose and glucose,

wherein there is more sucrose than glucose,

wherein the active ingredient is obtained by at least the following process:

solubilization of powder from Paeonia albiflora roots in water;

enzymatic hydrolysis;

separation of soluble and insoluble phases; and

enzymatic deactivation by heat treatment.

11. The method for filling in loss of structure and correcting for loosening of skin according to claim 10 , wherein the cosmetic composition is topically applied at least once daily.

12. The method for filling in loss of structure and correcting for loosening of skin according to claim 10 , wherein the cosmetic active ingredient is between 0.1 and 10% by total weight of the cosmetic composition.

Assignments (2)
CHANGE OF ADDRESS Recorded Jan 28, 2025
From: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
To: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
Reel/Frame 070028/0334 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 30, 2014
From: PAUFIQUE, JEAN
To: SOCIETE INDUSTRIELLE LIMOUSINE D'APPLICATION BIOLOGIQUE
Reel/Frame 034067/0305 →
Priority Claims (1)
FR 13 59109 · Sep 23, 2013 · national
Continuity (1)
Related Publication 20150086661A1 · Mar 26, 2015