IP Library Granted Patent US 9,308,308
Granted Patent B2
US 9,308,308 · App. 14/506,018 · Granted Apr 12, 2016

Methods of performing dialysis using an electrodeionization system

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Quick Facts
Patent No.
US 9,308,308
App. No.
14/506,018
Granted
Apr 12, 2016
Kind
B2
Abstract

Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source and an electrodeionization unit. The carbon source and urease source can be in the form of removable cartridges.

Claims (17)

1. A method of performing peritoneal dialysis comprising:

passing a spent dialysis fluid from an individual through a dialyzer, a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid, the dialyzer comprising an ion-rejection membrane selected from the group consisting of a first ion-rejection membrane that allows the passage of negatively charged ions and non-ionic species but restricts the passage of positively charged ions, and a second ion-rejection membrane that allows the passage of positively charged ions and non-ionic species but restricts the passage of negatively charged ions; and

returning the clean dialysis fluid to the individual.

2. The method of claim 1 , which includes passing the clean dialysis fluid through an ion exchange unit before the clean dialysis fluid returns to the patient.

3. The method of claim 1 , which includes adding at least one dialysis component to the clean dialysis fluid before the clean dialysis fluid returns to the individual.

4. The method of claim 1 , which includes passing the clean dialysis fluid through a filter before the clean dialysis fluid returns to the patient.

5. The method of claim 1 , which includes passing the clean dialysis fluid through an ultraviolet bactericidal light before the clean dialysis fluid returns to the patient.

6. A method of performing dialysis comprising:

passing a spent dialysis fluid through a dialysis compartment of a dialyzer comprising an ion-rejection membrane that allows the passage of negatively charged ions and non-ionic species but restricts the passage of positively charged ions, the ion-rejection membrane separating the dialysis compartment from a dialysate compartment of the dialyzer;

passing used dialysis fluid generated from the dialysate compartment of the dialyzer through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid;

adding a source of negative ions to the clean dialysis fluid; and

passing the clean dialysis fluid through the dialysate compartment of the dialyzer.

7. A method of performing dialysis comprising:

passing a spent dialysis fluid through a dialysis compartment of a dialyzer comprising an ion-rejection membrane that allows the passage of positively charged ions and non-ionic species but restricts the passage of negatively charged ions, the ion-rejection membrane separating the dialysis compartment from a dialysate compartment of the dialyzer;

passing used dialysis fluid generated from the dialysate compartment of the dialyzer through a carbon source, a urease source and an electrodeionization unit to produce a clean dialysis fluid;

adding a source of positive ions to the clean dialysis fluid; and

passing the clean dialysis fluid through the dialysate compartment of the dialyzer.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 074047/0336 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 074047/0822 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 26, 2015
From: DING, YUANPANG SAMUEL; MILLER, JOSHUA JAMES; ROHDE, JUSTIN; LO, YING-CHENG; KAROOR, SUJATHA
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE S.A.
Reel/Frame 035040/0889 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 26, 2015
From: DUPONT, STEPHANE
To: MILLAPORE SAS
Reel/Frame 035040/0956 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 26, 2015
From: MILLIPORE SAS
To: MILLIPORE CORPORATION
Reel/Frame 035041/0033 →