Methods for treating abnormal growths in the body using a flow reducing implant
View Patent ↗A flow reducing implant for reducing blood flow in a blood vessel having a cross sectional dimension, the flow reducing implant comprising a hollow element adapted for placement in the blood vessel defining a flow passage therethrough, said flow passage comprising at least two sections, one with a larger diameter and one with a smaller diameter, wherein said smaller diameter is smaller than a cross section of the blood vessel. A plurality of tabs anchor, generally parallel to the blood vessel wall, are provided in some embodiments of the invention.
1. An expandable flow-reducing implant for placement in a blood vessel of a patient, the implant comprising:
a narrowed section having first and second ends and defining a flow passage therethrough;
first and second flared sections located at the first and second ends of the narrowed section; and
one or more slits located on the narrowed section and the first and second flared sections,
wherein the one or more slits have a configuration that provides a greater stiffness to the narrowed section than the first and second flared sections, and wherein the one or more slits have a configuration that allows the first and second portions to expand to a diameter larger than the narrowed section.
2. The flow-reducing implant of claim 1 , wherein a diameter of the flow passage is substantially fixed at a size that is predetermined prior to implantation by a configuration of the one or more slits on the narrowed section.
3. The flow-reducing implant of claim 1 , wherein a configuration of the one or more slits on the first and second flared sections allow the first and second flared sections to expand within the blood vessel to a size that firmly affixes the implant within the blood vessel.
4. The flow-reducing implant of claim 1 , wherein the one or more slits on the narrowed section and/or the first and second flared sections are of varying width, thickness, density, length, and/or orientation.
5. The flow-reducing implant of claim 1 , wherein the one or more slits on the narrowed section and/or the first and second flared sections are of varying length.
6. The flow-reducing implant of claim 5 , wherein a length of the one or more slits increases as a function of a distance from a center of the narrowed section.
7. The flow-reducing implant of claim 1 , wherein the one or more slits of the first and second flared sections are on average larger than the one or more slits of the narrowed section.
8. The flow-reducing implant of claim 1 , wherein the one or more slits on the narrowed section and/or the first and second flared sections are non-uniform.
9. The flow-reducing implant of claim 1 , wherein the one or more slits on the narrowed section and/or the first and second flared sections are non-uniform before expansion of the first and second flared sections.
10. The flow-reducing implant of claim 1 , wherein the implant is coated with a biologically inert material.
11. The flow-reducing implant of claim 1 , wherein the one or more slits on the narrowed section and/or the first and second flared sections fill at least 80% of a surface of the flow-reducing implant.
12. The flow-reducing implant of claim 1 , wherein the implant is coated with materials that promote tissue ingrowth.
13. The flow-reducing implant of claim 1 , wherein the narrowed section is configured to decrease blood flow through the blood vessel.
14. The flow-reducing implant of claim 13 , wherein the blood vessel is a coronary sinus.
15. The flow-reducing implant of claim 14 , wherein the decrease in the blood flow through the coronary sinus is sufficient so as to cause angiogenesis.
16. The flow-reducing implant of claim 1 , wherein at least one of the flared sections expands as a result of a balloon expansion catheter.
17. The flow-reducing implant of claim 1 , wherein at least one of the flared sections expands automatically following removal of a restricting element.
18. The flow-reducing implant of claim 1 , wherein the first flared section has a first diameter and the second flared section has a second diameter, wherein the first diameter is larger than the second diameter.
19. The flow-reducing implant of claim 18 , wherein the first and second diameters are governed by the configuration of the one or more slits on the first and second flared sections.