IP Library Granted Patent US 9,327,127
Granted Patent B2
US 9,327,127 · App. 14/525,178 · Granted May 3, 2016

Selective high frequency spinal cord modulation for inhibiting pain with reduced side effects, and associated systems and methods

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Quick Facts
Patent No.
US 9,327,127
App. No.
14/525,178
Granted
May 3, 2016
Kind
B2
Abstract

Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region to address low back pain without creating unwanted sensory and/or motor side effects. In other embodiments, modulation in accordance with similar parameters can be applied to other spinal or peripheral locations to address other indications.

Claims (31)

1. A method for treating a patient, comprising:

delivering an electrical signal to the patient's spinal cord via at least one implantable signal delivery device; and

wherein the electrical signal has a frequency of from 1.5 kHz to 50 kHz and does not create paresthesia in the patient.

2. The method of claim 1 wherein the electrical signal is delivered to the patient to treat pain in the patient.

3. The method of claim 2 wherein the pain in the patient includes pain associated with chronic regional pain syndrome.

4. The method of claim 3 , further comprising placing the at least one signal delivery device at a cervical vertebral level.

5. The method of claim 4 wherein the cervical vertebral level is from about C3 to about C7, inclusive.

6. The method of claim 2 wherein the pain in the patient includes total body pain.

7. The method of claim 6 , further comprising placing the at least one signal delivery device at a cervical vertebral level.

8. The method of claim 7 wherein the cervical vertebral level is from about C3 to about C7, inclusive.

9. The method of claim 2 wherein the pain in the patient includes pain associated with shingles.

10. The method of claim 9 , further comprising placing the at least one signal delivery device at a thoracic vertebral level.

11. The method of claim 2 wherein the pain in the patient includes at least one of low-back pain and leg pain.

12. The method of claim 2 wherein the pain in the patient includes both low-back pain and leg pain.

13. The method of claim 2 wherein the pain in the patient includes nociceptive pain.

14. The method of claim 2 wherein the pain in the patient includes pain from surgery.

15. The method of claim 1 wherein the at least one signal delivery device is a single electrical lead having a single axial row of electrical contacts.

16. The method of claim 15 wherein the electrical signal is delivered to treat pain in the patient, and wherein the pain in the patient includes bilateral pain.

17. The method of claim 1 , further comprising placing the at least one signal delivery device at a position along the patient's spinal cord as at least part of a placement process, without using patient feedback during the placement process to at least assist in selecting the position.

18. The method of claim 17 wherein placing includes placing the at least one signal delivery device at a position having an axial location and a lateral location without using patient feedback to adjust one of (a) the axial location of the at least signal delivery device, or (b) the lateral location of the at least one signal delivery device.

19. The method of claim 1 wherein the electrical signal has a frequency of from 5 kHz to 15 kHz.

20. The method of claim 1 wherein the electrical signal has a frequency of from 3 kHz to 15 kHz.

21. The method of claim 1 wherein the electrical signal has a frequency of from 3 kHz to 20 kHz.

22. The method of claim 1 wherein the electrical signal has a frequency of from 3 kHz to 10 kHz.

23. The method of claim 1 wherein the electrical signal has a frequency of 10 kHz.

24. The method of claim 1 wherein the at least one signal delivery device is positioned at a location laterally offset from a midline of the patient's spinal cord, and wherein the electrical signal is delivered to treat pain in the patient, and wherein the pain in the patient includes bilateral pain.

25. The method of claim 1 , further comprising implanting the at least one signal delivery device at a position along the patient's spinal cord.

26. The method of claim 1 wherein the at least one signal delivery device is a paddle.

27. A method for treating a patient, comprising:

activating a signal generator to apply an electrical signal to the patient's spinal cord via at least one implantable signal delivery device; and

wherein the electrical signal has a frequency of from 1.5 kHz to 50 kHz and does not create paresthesia in the patient.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded Apr 4, 2025
From: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
To: NEVRO CORP.
Reel/Frame 070743/0001 →
PATENT SECURITY AGREEMENT Recorded Dec 1, 2023
From: NEVRO CORP.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 065744/0302 →
CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING PARTY DATA NAME PREVIOUSLY RECORDED ON REEL 034045 FRAME 0426. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Nov 22, 2016
From: ALATARIS, KONSTANTINOS; WALKER, ANDRE B.; PARKER, JON; CHITRE, YOUGANDH; PARK, SANGSOO WESLEY; THACKER, JAMES R.
To: NEVRO CORP.
Reel/Frame 040671/0287 →
RELEASE OF SECURITY INTEREST Recorded Jun 27, 2016
From: CRG SERVICING LLC
To: NEVRO CORP.
Reel/Frame 039168/0890 →
ASSIGNMENT AGREEMENT (REAFFIRMATION) Recorded Jun 13, 2016
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: CRG SERVICING LLC,
Reel/Frame 038984/0865 →
SECURITY INTEREST Recorded Dec 12, 2014
From: NEVRO CORP.
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 034619/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2014
From: ALATARIS, KONSTANTINOS; WALKER, ANDRE B.; PARKER, JON; CHITRE, YOUGANDH; PARK, SANGSOO WESLEY; THACKER, JAMES R.
To: NEVRO CORPORATION
Reel/Frame 034045/0426 →