IP Library Granted Patent US 9,421,066
Granted Patent B2
US 9,421,066 · App. 14/530,002 · Granted Aug 23, 2016

System and method for visualizing tissue during ablation procedures

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Quick Facts
Patent No.
US 9,421,066
App. No.
14/530,002
Granted
Aug 23, 2016
Kind
B2
Abstract

Systems for visualizing cardiac tissue during an ablation procedure are provided. In general, the systems include an imaging module configured to measure absorbance data at first and second wavelengths wherein the ratio of these absorbance values identifies the nature of the tissue (e.g., lesion, de novo tissue, etc.). The imaging module can also include a video system having at least two chips with corresponding bandpass filters centered at the first and second target wavelengths. The system can also include a processor and/or video monitor for combining the images produced by the various chips, determining treated and non-treated tissue based on the ratio of absorbance values at the target wavelengths, and displaying images of the treatment area. Methods of visualizing cardiac treatment areas during ablation procedures are also provided herein.

Claims (18)

1. A method of treating atrial fibrillation, comprising:

delivering a distal portion of an ablation catheter to a position adjacent an ostium of a pulmonary vein;

irradiating a partial ring of tissue along the ostium via an illumination source slidably disposed within a lumen of the ablation catheter;

comparing a first amount of light reflected by the partial ring of tissue at a first, predetermined wavelength to a second amount of light reflected by the partial ring of tissue at a second, predetermined wavelength;

classifying the partial ring of tissue as a lesion or as de novo tissue if the first amount of light is less than or greater than the second amount of light, respectively; and

ablating the partial ring of tissue if classified as de novo tissue.

2. The method of claim 1 , wherein the first, predetermined waveband is centered at about 550 nm, and the second predetermined waveband is centered at about 560 nm.

3. The method of claim 1 , further comprising displaying a real-time image of the tissue area with a type of false-coloring indicative of a treatment status.

4. The method of claim 3 , wherein the false coloring is indicative of a lesion.

5. The method of claim 1 , further comprising repeating the irradiating, comparing, classifying, and ablating steps for each of a plurality of partial rings of tissue thereby providing a substantially continuous lesion around the ostium of the pulmonary vein.

6. The method of claim 1 , further comprising displaying a real-time image of the ostium of the pulmonary vein on a video monitor.

7. The method of claim 6 , wherein the real-time image indicates partial rings as lesions or as de novo tissue.

8. The method of claim 7 , wherein lesions are indicated by a type of false coloring.

9. The method of claim 6 , wherein the image is taken along a longitudinal axis of the catheter.

10. The method of claim 1 , wherein the step of comparing a first amount of light reflected by the partial ring of tissue includes the use of a reflectivity sensor.

11. The method of claim 10 , wherein the reflectivity sensor comprises an endoscope.

12. The method of claim 10 , further including an imaging module that is in communication with the reflectivity sensor and is configured to receive at least one of absorbance signals/data and reflectivity signals/data from the reflectivity sensor.

13. The method of claim 12 , further including an image splitter that receives data from the reflectivity sensor and is configured to split an image into a desired number of images.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded May 16, 2019
From: GPB DEBT HOLDINGS II, LLC
To: CARDIOFOCUS, INC.
Reel/Frame 049200/0597 →
RELEASE OF SECURITY INTEREST Recorded May 10, 2019
From: SILICON VALLEY BANK; OXFORD FINANCE LLC
To: CARDIOFOCUS, INC.
Reel/Frame 049138/0233 →
RELEASE OF SECURITY INTEREST Recorded May 10, 2019
From: SILICON VALLEY BANK; SOLAR CAPITAL LTD.
To: CARDIOFOCUS, INC.
Reel/Frame 049138/0362 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded May 10, 2019
From: CARDIOFOCUS, INC.
To: KENNEDY LEWIS INVESTMENT MANAGEMENT LLC
Reel/Frame 049149/0356 →
RELEASE OF SECURITY INTEREST Recorded May 9, 2019
From: SILICON VALLEY BANK; OXFORD FINANCE LLC
To: CARDIOFOCUS, INC.
Reel/Frame 049133/0474 →
SECURITY INTEREST Recorded Apr 9, 2018
From: CARDIOFOCUS, INC.
To: GPB DEBT HOLDINGS II LLC
Reel/Frame 045478/0532 →
SECURITY INTEREST Recorded Mar 31, 2017
From: CARDIOFOCUS, INC.
To: SILICON VALLEY BANK; SOLAR CAPITAL LTD.
Reel/Frame 041805/0976 →
SECURITY AGREEMENT Recorded Apr 24, 2015
From: CARDIOFOCUS, INC.
To: SILICON VALLEY BANK; OXFORD FINANCE LLC
Reel/Frame 035497/0393 →
FIRST AMENDMENT TO INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 18, 2014
From: CARDIOFOCUS, INC.
To: SILICON VALLEY BANK; OXFORD FINANCE LLC
Reel/Frame 034283/0346 →