IP Library Granted Patent US 9,603,516
Granted Patent B2
US 9,603,516 · App. 14/531,926 · Granted Mar 28, 2017

Objective quality metric for ocular wavefront measurements

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Quick Facts
Patent No.
US 9,603,516
App. No.
14/531,926
Granted
Mar 28, 2017
Kind
B2
Abstract

A system and method for determining an objective quality metric for image data collected by a wavefront aberrometer. The method may include quantifying a plurality of characteristics of the image data and calculating the objective quality metric based on the quantified characteristics of the image data. The objective quality metric can be a weighted sum of the quantified characteristics of the image data. The weightings for the weighted sum can be determined based on subjective quality metrics assigned to a set of training image data by a human expert.

Claims (55)

1. An ophthalmic device, comprising:

a wavefront aberrometer; and

a processing module enabled to execute computer-executable instructions for,

receiving an indication of a plurality of wavefront aberrometer images indicative of ocular aberrations of an eye of a patient;

determining a plurality of quantitative quality metrics respectively for each of the wavefront aberrometer images, wherein each of the quantitative quality metrics is based on a characteristic of a respective wavefront aberrometer image;

selecting at least a subset of the wavefront aberrometer images based on values of the quantitative quality metrics; and

determining ocular aberration measurements using at least the subset of the wavefront aberrometer images.

2. The ophthalmic device of claim 1 , wherein the subset of wavefront aberrometer images consists of a first wavefront aberrometer image.

3. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

calculating a first quantitative quality metric using a parameter determined from a plurality of training images representative of ocular aberrations.

4. The ophthalmic device of claim 3 , further comprising computer-executable instructions for:

determining the parameter based on qualitative quality metrics assigned to the plurality of training images by a human expert.

5. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristic of a second wavefront aberrometer image by analyzing a spatial-domain representation of the second wavefront aberrometer image.

6. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristic of a third wavefront aberrometer image by analyzing a frequency-domain representation of the third wavefront aberrometer image.

7. The ophthalmic device of claim 1 , further comprising computer-executable instructions for: quantifying the characteristic of a fourth wavefront aberrometer image as an output of a mathematical function that receives the fourth wavefront aberrometer image as an input.

8. The ophthalmic device of claim 7 , further comprising computer-executable instructions for:

determining a quantitative quality metric for the fourth wavefront image based on a combination of outputs of a plurality of mathematical functions.

9. The ophthalmic device of claim 8 , further comprising computer-executable instructions for:

calculating the combination of the outputs of the mathematical functions based on a weighted sum of the outputs calculated using respective weightings of the mathematical functions.

10. The ophthalmic device of claim 9 , further comprising computer-executable instructions for:

selecting the weightings based on qualitative quality metrics assessed to a plurality of test images by a human expert.

11. The ophthalmic device of claim 10 , further comprising computer-executable instructions for:

selecting the weightings based on a difference between the quantitative quality metrics calculated for the test images and the qualitative quality metrics for the test images.

12. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristic of a fifth wavefront aberrometer image based on a degree of centration of the fifth wavefront aberrometer image.

13. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristics of the subset of wavefront aberrometer images based on a first variance of the ocular aberration measurements.

14. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristic of a sixth wavefront aberrometer image based on a width of a spectral peak identified in a spatial frequency-domain representation of the sixth wavefront aberrometer image.

15. The ophthalmic device of claim 14 , further comprising computer-executable instructions for:

determining the characteristic of the sixth wavefront aberrometer image based on a second variance of the width of the spectral peak based on a direction across the spectral peak.

16. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

determining the characteristic of a seventh wavefront aberrometer image based on an image contrast value for the seventh wavefront aberrometer image.

17. The ophthalmic device of claim 16 , further comprising computer-executable instructions for:

determining the image contrast value from a region of interest within the seventh wavefront aberrometer image.

18. The ophthalmic device of claim 1 , wherein an eighth wavefront aberrometer image comprises a Moiré fringe pattern.

19. The ophthalmic device of claim 1 , wherein a ninth wavefront aberrometer image comprises a Shack-Hartmann spot pattern.

20. The ophthalmic device of claim 1 , wherein the ocular aberration measurements include measurements selected from: a spherical power of the eye, a cylindrical power of the eye, and a cylindrical axis of the eye.

21. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

based on the ocular aberration measurements, selecting an intraocular lens for implantation in the eye.

22. The ophthalmic device of claim 1 , further comprising computer-executable instructions for:

outputting the ocular aberration measurements for positioning an intraocular lens during cataract surgery.

23. A computer-implemented method for execution in a wavefront aberrometer system, the method comprising:

receiving an indication of a plurality of wavefront aberrometer images indicative of ocular aberrations of an eye of a patient;

determining a plurality of quantitative quality metrics respectively for each of the wavefront aberrometer images, wherein each of the quantitative quality metrics is based on a characteristic of a respective wavefront aberrometer image;

selecting at least a subset of the wavefront aberrometer images based on values of the quantitative quality metrics; and

determining ocular aberration measurements using at least the subset of the wavefront aberrometer images.

24. A computer-readable medium storing instructions executable by a computer for:

receiving an indication of a plurality of wavefront aberrometer images indicative of ocular aberrations of an eye of a patient;

determining a plurality of quantitative quality metrics respectively for each of the wavefront aberrometer images, wherein each of the quantitative quality metrics is based on a characteristic of a respective wavefront aberrometer image;

selecting at least a subset of the wavefront aberrometer images based on values of the quantitative quality metrics; and

determining ocular aberration measurements using at least the subset of the wavefront aberrometer images.

25. The ophthalmic device of claim 1 , wherein the quantitative quality metrics comprise scalar values.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
MERGER Recorded Feb 9, 2017
From: WAVETEC VISION SYSTEMS, INC.
To: ALCON RESEARCH, LTD.
Reel/Frame 041671/0059 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2017
From: ALCON RESEARCH, LTD.
To: NOVARTIS AG
Reel/Frame 041671/0398 →