Dehydration device and methods for drying biological materials
This invention relates generally to a dehydration device and methods for drying biological materials to produce dried biological materials having enhanced structural properties. More specifically, the invention relates to a dehydration device and related methods for drying biological tissue to produce enhanced tissue grafts.
1. A dehydration device for use in drying biological material, comprising:
a drying housing defining a drying chamber having walls, at least one of the walls defining inflow apertures and at least one of the walls defining outflow apertures;
an inflow plenum in communication with the inflow apertures;
an outflow plenum in communication with the outflow apertures; and
an air-moving assembly configured to deliver air to the inflow plenum and receive the return air from the outflow plenum;
wherein in use the biological material is placed into the drying chamber to dehydrate the biological material.
2. The dehydration device of claim 1 , wherein the inflow and outflow plenums are integrally formed with the drying housing and the inflow and outflow apertures are provided by arrays of uniformly arranged and aligned apertures.
3. The dehydration device of claim 1 , further comprising an air-heating assembly configured to selectively heat the air delivered to the inflow plenum.
4. The dehydration device of claim 1 , further comprising a control system configured to control the operating parameters of the device to dry the biological material.
5. The dehydration device of claim 1 , wherein the drying chamber is maintained at a humidity of less than 10%.
6. The dehydration device of claim 1 , wherein the air delivered by the air-moving assembly is an inert gas.
7. The dehydration device of claim 1 , wherein two or more biological materials are placed into the drying chamber to be dehydrated at the same time.
8. The dehydration device of claim 1 , wherein the biological material is placental tissue.
9. A dehydration device for use in drying biological materials, comprising:
a drying housing defining a drying chamber having walls, at least one of the walls defining inflow apertures and at least one of the walls defining outflow apertures;
an inflow plenum in communication with the inflow apertures;
an outflow plenum in communication with the outflow apertures;
an air-moving assembly configured to deliver air to the inflow plenum and receive the return air from the outflow plenum;
an air-heating assembly configured to selectively heat the air delivered to the inflow plenum; and
a control system configured to control the operating parameters of the device to dry the biological materials;
wherein in use the biological material is placed into the drying chamber and the control system is operated to deliver heated air to the drying chamber to dehydrate the biological material.
10. A tissue graft having enhanced structural propertied prepared by dehydrating a placental tissue using the dehydration device of claim 1 .
11. The dehydration device of claim 2 , wherein the integrally formed inflow plenum, outflow plenum, and drying housing are configured to provide an even distribution of at least one of pressure, flow, or temperature of the air flowing through the drying chamber.
12. The dehydration device of claim 3 , wherein the air-heating assembly comprises an electric-resistance heating element.