IP Library › Granted Patent US 9,358,231
Granted Patent B2
US 9,358,231 · App. 14/552,229 · Granted Jun 7, 2016

Type II RAF kinase inhibitors

Inventors: Nathanael Gray (Boston, MA); Hwan Geun Choi (Chestnut Hill, MA); Xianming Deng (Brookline, MA); Jianming Zhang (Cambridge, MA); Izidore Lossos (Aventura, FL)
Assignees: Dana-Farber Cancer Institute, Inc.; University of Miami
A61K31/496C07D239/42C07D401/12C07D401/14C07D403/12C07D417/12C07D471/04C07D487/04
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Quick Facts
Patent No.
US 9,358,231
App. No.
14/552,229
Granted
Jun 7, 2016
Kind
B2
Abstract

The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.

Claims (2)

1. A method of treating lymphoma in a subject comprising administering to the subject a compound of formula:

or a pharmaceutically acceptable salt thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2015
From: LOSSOS, IZIDORE
To: UNIVERSITY OF MIAMI
Reel/Frame 034750/0060 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2014
From: GRAY, NATHANAEL S.; CHOI, HWAN G.; ZHANG, JIANMING; DENG, XIANMING
To: DANA-FARBER CANCER INSTITUTE, INC.
Reel/Frame 034486/0071 →
Continuity (3)
Continuation 13519826
Provisional Application 61290884 · Dec 29, 2009
Related Publication 20150157629A1 · Jun 11, 2015