System and method for locating neural tissue
An example of a system comprises a patch of electrodes for placement on tissue containing neural tissue, and a tissue tester configured to measure an electrical characteristic of tissue. The tissue tester may include a test controller and switches. The test controller and the switches may be configured to connect different combinations of the electrodes to create subsets of two or more electrodes to measure the electrical characteristic of tissue using the subsets. The test controller may be configured to measure an electrical characteristic of tissue using the subsets within the set of electrodes placed on the tissue, and compare measurements of the electrical characteristic and identify a neural target for a therapy based on the comparison of the measurements of the electrical characteristic for tissue at the neural target relative to adjacent non-neural tissue.
1. A method for identifying a neural target, comprising:
implanting a patch of electrodes, including placing a set of electrodes on tissue containing neural tissue, the set of electrodes including subsets of two or more electrodes;
measuring an electrical characteristic of tissue using the subsets within the set of electrodes placed on the tissue, the electrical characteristic of tissue quantifying an ability of the tissue to oppose or to conduct an electric current or an ability of the tissue to transmit an electric field; and
comparing measurements and identifying a subset of electrodes that that provides a more desirable measurement of the electrical characteristic than other subsets of electrodes to identify the neural target, wherein the more desirable measurement is a measurement that has a lower ability to oppose the electric current, or a higher ability to conduct the electric current, or a higher ability to transmit an electric field.
2. The method of claim 1 , wherein identifying the subset of electrodes that has a more desirable measurement of the electrical characteristic includes identifying the subset of electrodes that has the lowest tissue impedance or tissue resistance to identify the neural target.
3. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on tissue in a carotid sinus region.
4. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on a baroreceptor region.
5. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on tissue containing a peripheral nerve trunk.
6. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on tissue containing autonomic neural tissue.
7. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on a cardiac fat pad.
8. The method of claim 1 , wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on tissue in a pulmonary artery region.
9. The method of claim 1 ; wherein placing the set of electrodes on tissue containing neural tissue includes placing the set of electrodes on tissue containing motor neural tissue.
10. The method of claim 1 , further comprising confirming the neural target, wherein confirming the neural target includes:
stimulating the neural target; and
monitoring a physiological response confirming stimulation of the neural target.
11. The method of claim 10 , further comprising monitoring for undesired capture of adjacent tissue.
12. The method of claim 1 , further comprising recording the measurements for each of the subsets.