IP Library Granted Patent US 9,522,123
Granted Patent B2
US 9,522,123 · App. 14/579,061 · Granted Dec 20, 2016

Use of one or a combination of phyto-cannabinoids in the treatment of epilepsy

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Quick Facts
Patent No.
US 9,522,123
App. No.
14/579,061
Granted
Dec 20, 2016
Kind
B2
Abstract

This invention relates to the use of one or more cannabinoids in the treatment of epilepsy and more particularly to the use of one or a combination of cannabinoids in the treatment of generalized or partial seizure. In one embodiment it relates to the use of the cannabinoid THCV, as a pure or isolated compound, or as a plant extract in which significant amounts of any THC naturally present has been selectively removed. In another embodiment the phytocannabinoid is CBD.

Claims (13)

1. A method of treating complex partial seizure comprising administering cannabidiol (CBD) to a patient wherein the CBD is present in an amount which provides a daily dose of at least 400 mg.

2. The method of claim 1 , wherein CBD is present in an amount which provides a daily dose of from 400 to 800 mg.

3. The method of claim 1 , wherein the CBD is used in combination with tetrahydrocannabivarin (THCV).

4. The method of claim 3 , wherein the THCV is present in an amount which provides a daily dose of at least 1.5 mg.

5. The method of claim 4 , wherein the THCV is present in an amount which provides a daily dose of at least 15 mg.

6. The method of claim 1 , wherein the CBD is present as a plant extract.

7. The method of claim 6 , wherein the plant extract comprises less than 5% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract.

8. The method of claim 7 , wherein the plant extract comprises less than 1% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract.

9. The method of claim 1 , wherein the CBD is present as a pure or isolated cannabinoid.

10. The method of claim 3 , wherein the CBD in combination with THCV is present as a plant extract.

11. The method of claim 10 , wherein the plant extract comprises less than 5% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract.

12. The method of claim 11 , wherein the plant extract comprises less than 1% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract.

13. The method of claim 3 , wherein the CBD in combination with THCV is present as a pure or isolated cannabinoid.

Assignments (5)
CHANGE OF NAME Recorded May 13, 2025
From: GW PHARMA LIMITED
To: JAZZ PHARMACEUTICALS OPERATIONS UK LIMITED
Reel/Frame 071104/0173 →
SECURITY AGREEMENT Recorded Jul 22, 2021
From: GW PHARMA LIMITED; GW RESEARCH LIMITED
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 056958/0493 →
REMOVE PAT NO 9,066,920 AT REEL/FRAME 044162/0001 -- THE DEED OF ASSIGNMENT RECORDED AT REEL/FRAME 044162/0001 DID NOT CONVEY PAT NO 9,066,920 Recorded Nov 7, 2018
From: OTSUKA PHARMACEUTICAL CO., LIMITED
To: GW PHARMA LIMITED
Reel/Frame 048407/0325 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2017
From: OTSUKA PHARMACEUTICAL CO., LIMITED
To: GW PHARMA LIMITED
Reel/Frame 044162/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2016
From: WHALLEY, BENJAMIN; STEPHENS, GARY; WILLIAMS, CLAIRE; GUY, GEOFFREY; WRIGHT, STEPHEN; KIKUCHI, TETSURO
To: GW PHARMA LIMITED; OTSUKA PHARMACEUTICAL CO., LIMITED
Reel/Frame 037767/0204 →