IP Library Granted Patent US 9,458,156
Granted Patent B2
US 9,458,156 · App. 14/580,355 · Granted Oct 4, 2016

Tricyclic compounds as anticancer agents

Inventors: Derek J. Norris (Pennington, NJ); George V. Delucca (Pennington, NJ); Ashvinikumar V. Gavai (Princeton Junction, NJ); Francis Y. Lee (Yardley, PA); John S. Tokarski (Princeton, NJ)
Assignee: Bristol-Myers Squibb Company
C07D471/04A61K31/437
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Quick Facts
Patent No.
US 9,458,156
App. No.
14/580,355
Granted
Oct 4, 2016
Kind
B2
Abstract

The present invention is directed to tricyclic compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

Claims (4)

1. A compound of the formula

or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof.

2. A pharmaceutical composition which comprises a compound according to claim 1 or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable carriers, diluents or excipients.

3. A method of treating cancer comprising administering a therapeutically effective amount of a compound according to claim 1 or a pharmaceutically acceptable salt thereof wherein the cancer is small cell lung cancer, non-small cell lung cancer, colorectal cancer, multiple myeloma or AML.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2015
From: MANDAL, SUNIL KUMAR
To: SYNGENE INTERNATIONAL LIMITED
Reel/Frame 035728/0566 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2015
From: SYNGENE INTERNATIONAL LIMITED
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 035728/0607 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2015
From: NORRIS, DEREK J.; DELUCCA, GEORGE V.; GAVAI, ASHVINIKUMAR V.; QUESNELLE, CLAUDE A.; GILL, PATRICE; O'MALLEY, DANIEL; VACCARO, WAYNE; LEE, FRANCIS Y.; DEBENEDETTO, MIKKEL V.; DEGNAN, ANDREW P.; FANG, HAIQUAN; HILL, MATTHEW D.; HUANG, HONG; SCHMITZ, WILLIAM D.; STARRETT, JOHN E., JR.; HAN, WEN-CHING; TOKARSKI, JOHN S.
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 035728/0889 →
Continuity (1)
Related Publication 20160176864A1 · Jun 23, 2016