Ion mobility spectrometer and method of using the same

1. A method of detecting constituents in a sample, said method comprising:

channeling a sample gas stream to be tested for constituents into an ionization region;

generating a plurality of ions in the ionization region;

substantially preventing the plurality of ions in the ionization region from flowing into a drift region coupled to the ionization region through inducing a first voltage in a device positioned between the ionization region and the drift region; and

injecting at least a portion of the ions from the ionization region into the drift region comprising:

regulating the voltage in the device to a second voltage for a first predetermined temporal period, the second voltage less than the first voltage;

regulating the voltage in the device to the first voltage; and

regulating the voltage in the device to the second voltage for a second predetermined temporal period, the second predetermined temporal period different from the first predetermined temporal period.

2. The method in accordance with claim 1 , wherein substantially preventing the plurality of ions in the ionization region from flowing comprises energizing an ion gate device.

3. The method in accordance with claim 1 , wherein regulating the electric field to a second voltage comprises de-energizing an ion gate device.

4. The method in accordance with claim 1 , wherein regulating the voltage in the device to a second voltage for a first predetermined temporal period comprises transmitting a first ion injection pulse having a first pulse width from a pulse control device to an ion gate device.

5. The method in accordance with claim 4 , wherein transmitting a first ion injection pulse having a first pulse width comprises enhancing detection of high-mobility ions.

6. The method in accordance with claim 5 , wherein enhancing detection of high-mobility ions comprises generating a first spectral trace including a plurality of resolved high-mobility ion peaks.

7. The method in accordance with claim 4 , wherein regulating the voltage of the device to the second voltage for a second predetermined temporal period comprises transmitting a second ion injection pulse having a second pulse width from the pulse control device to the ion gate device, the second pulse width greater than the first pulse width.

8. The method in accordance with claim 7 , wherein transmitting a second ion injection pulse having a second pulse width comprises enhancing detection of low-mobility ions.

9. The method in accordance with claim 8 , wherein:

transmitting a first ion injection pulse having a first pulse width to a pulse control device comprises generating a first spectral trace including a low-mobility ion peak having a first amplitude; and

enhancing detection of low-mobility ions comprises generating the second spectral trace including a second low-mobility ion peak having a second amplitude greater than the first amplitude.

10. The method in accordance with claim 1 , wherein injecting at least a portion of the ions from the ionization region into the drift region comprises alternating generation of ion spectra with the second voltage for the first predetermined temporal period and the second voltage for the second predetermined temporal period at a predetermined frequency.

11. An apparatus for detecting constituents in a sample, said apparatus comprising:

a casing;

an ionization region at least partially defined by said casing, said ionization region configured to generate ions;

a drift region at least partially defined by said casing;

an ion gate device positioned between said ionization region and said drift region, said ion gate device configured to facilitate prevention of the plurality of ions in said ionization region from flowing into said drift region through inducing a first voltage in said ion gate device; and

a control system coupled to said ionization chamber, said control system comprising a processor, said control system configured to:

regulate the voltage in said ion gate device to a second voltage for a first predetermined temporal period and inject a first portion of the ions from said ionization region into said drift region, the second voltage less than the first voltage;

regulate the voltage in said ion gate device to the first voltage; and

regulate the voltage in said ion gate device to the second voltage for a second predetermined temporal period and inject a second portion of the ions from said ionization region into said drift region, the second predetermined temporal period different from the first predetermined temporal period.

12. The apparatus in accordance with claim 11 further comprising:

an ion detector positioned downstream of said drift region; and

a spectral analysis device coupled to said ion detector, said spectral analysis device configured to generate a detection spectrum representative of ions detected at said ion detector.

13. The apparatus in accordance with claim 12 , wherein:

said control system further comprises a pulse control device coupled to said processing device, said control system further configured to transmit a first ion injection pulse having a first pulse width from said pulse control device to said ion gate device, thereby enhancing detection of high-mobility ions by said ion detector; and

said spectral analysis device configured to generate a first spectral trace including a plurality of resolved high-mobility ion peaks.

14. The apparatus in accordance with claim 13 , wherein:

said control system further configured to transmit the first ion injection pulse having the first pulse width from said pulse control device to said ion gate device, thereby facilitating generation of a first spectral trace including a low-mobility ion peak having a first amplitude; and

said control system further configured to transmit a second ion injection pulse having a second pulse width from said pulse control device to said ion gate device, thereby enhancing detection of the low-mobility ions by said ion detection through generation of a second spectral trace including a second low-mobility ion peak having a second amplitude greater than the first amplitude.

15. The apparatus in accordance with claim 11 , wherein said ion gate device configured to de-energize to inject the first portion of the ions and the second portion of the ions from said ionization region into said drift region.

16. The apparatus in accordance with claim 11 , wherein said control system further comprises a pulse control device coupled to said processing device and said ion gate device, said processing device further configured to regulate the voltage in said ion gate device to the second voltage for the first predetermined temporal period through transmission of a first ion injection pulse having a first pulse width from said pulse control device to said ion gate device.

17. The apparatus in accordance with claim 16 , wherein the second predetermined temporal period is different from the first predetermined temporal period, said control system further configured to transmit a second ion injection pulse having a second pulse width from said pulse control device to said ion gate device, the second pulse width greater than the first pulse width.

18. The apparatus in accordance with claim 11 , wherein said control system further configured to alternate generation of ion spectra with the second voltage for the first predetermined temporal period and the second voltage for the second predetermined temporal period at a predetermined frequency.

19. One or more computer readable storage media having computer-executable instructions embodied thereon, wherein when executed by at least one processor, the computer-executable instructions cause the processor to:

regulate a voltage generated in an ion gate device to a first voltage, the ion gate device positioned between an ionization region and a drift region in an ion mobility spectrometer (IMS) detection system, thereby facilitating prevention of a plurality of ions flowing from the ionization region;

regulate the voltage generated in the ion gate device to a second voltage for a first predetermined temporal period, the second voltage less than the first voltage, thereby facilitating injection of a first portion of the ions from the ionization region into the drift region;

regulate the electric field to back to the first voltage; and

regulate the electric field to the second voltage for a second predetermined temporal period, thereby facilitating injection of a second portion of the ions from the ionization region into the drift region, the second predetermined temporal period different from the first predetermined temporal period.

20. The one or more computer readable storage media in accordance with claim 19 , wherein when executed by at least one processor, the computer-executable instructions further cause the processor to:

transmit a first ion injection pulse having a first pulse width from a pulse control device to the ion gate device, thereby enhancing detection of high-mobility ions with an ion detector positioned downstream of the drift region through generating a first spectral trace including a plurality of resolved high-mobility ion peaks with a spectral analysis device coupled to the ion detector, the spectral analysis device configured to generate a detection spectrum representative of ions detected at the ion detector, and thereby generating the first spectral trace including a first low-mobility ion peak having a first amplitude; and

transmit a second ion injection pulse having a second pulse width from the pulse control device to the ion gate device, the second pulse width greater than the first pulse width, thereby enhancing detection of low-mobility ions through generating a second spectral trace including a second low-mobility ion peak having a second amplitude greater than the first amplitude.