IP Library Granted Patent US 10,665,344
Granted Patent B2
US 10,665,344 · App. 14/589,256 · Granted May 26, 2020

Personalized management and comparison of medical condition and outcome based on profiles of community patients

Inventors: Benjamin Heywood (Cambridge, MA); Jeff Cole (Cambridge, MA); James Heywood (Cambridge, MA)
Assignee: PatientsLikeMe, Inc.
G16H50/20A61B5/0002A61B5/4824A61B5/4833G06F19/325G06Q50/22G06Q50/24G16H10/20G16H10/60G16H15/00G16H40/63G16H50/50G16H50/70G06F19/3456G06F19/3481
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Quick Facts
Patent No.
US 10,665,344
App. No.
14/589,256
Granted
May 26, 2020
Kind
B2
Abstract

The invention can be directed toward a method for personalized management and comparison of medical condition and outcome based on patient profiles of a community of patients. The method can include the steps of providing a database of patient profiles, providing a user interface for inputting a query of the database from a user, generating a query result including one or more matching patient profiles from the database, and displaying the query result as a correlation medical condition parameters of the user with a medical outcome.

Claims (18)

1. A computer web server coupled to a plurality of network coupled client computer devices configured to provide a GUI on each network client computer device wherein each client computer is associated with a respective patient of a community of patients, comprising:

a plurality of web based databases configured to store medical related data associated with the community of patients wherein each of the plurality of the web based databases encodes a data structure storing a patient's unique identifier and patient provided information which encoded data structure is configured to be networked transferred to a client computer;

a processor disposed in communication with the plurality of databases, wherein the processor upon execution of instructions is configured to establish network communication with one or more client computers so as to:

provide a graphical user interface on each client computer coupled to the web server through interaction with web server, the graphical user interface allowing one or more patients within the online community of patients to input information regarding diseases of the one or more patients, interventions employed by the one or more patients to treat the diseases, and symptoms experienced by the one or more patients before and after the interventions are employed;

transmit an online request from a client computer to the web server to initiate an online clinical study in the web based server to determine the efficacy of an intervention;

collect information, on the web server and store in one or more of the web based databases, regarding a disease of the one or more patients and a particular intervention employed by the one or more patients to treat the disease, the information having been input by the one or more patients via the graphical user interface on one of the plurality of client computers;

collect information, on the web server and store in one or more of the web based databases, regarding symptoms experienced by the one or more patients before the particular intervention is employed by the one or more patients to treat the disease, the information having been input by the one or more patients via the graphical user interface on one of the plurality of client computers and further collect information from the one or more patients after a subset of the patients employs a remedy to treat the disease;

collect information, on the web server and store in one or more of the web based databases, regarding symptoms experienced by the one or more patients after the particular intervention was employed by the one or more patients to treat the disease, the information having been input by the one or more patients via the graphical user interface on one of the plurality of client computers;

analyze the information, regarding the disease of the one or more patients in the web server coupled to the plurality of client computers, the particular intervention employed by the one or more patients to treat the disease, and the symptoms experienced by the one or more patients before and after the particular intervention is employed to determine the efficacy of the particular intervention in treating the disease by comparing the efficacy of the particular intervention with data from one or more control patients within the community of patients on the web based server computer;

determine, in the web server, one or more alternative interventions that were employed by other patients that experienced one or more side effects when employing the particular intervention;

determine, in the web server, pharmacokinetic data from the patient provided data;

processing an online request from the patient to modify a composition of a subset of other patients wherein the composition of the subset of other patients is defined by a scalar-vector decomposition on a matrix of similarities of attributes of the subset of other patients; and

causing a GUI to be displayed on one or more of the client computer devices displaying one or more alternative interventions and the determined efficacy of the particular intervention wherein the GUI provides a single display screen that is user manipulable to aggregate and filter data in accordance with pre-intervention and post intervention treatments to illustrate the determined efficacy of the particular intervention and utilizing the determined pharmacokinetic data, cause a pharmacokinetic curve to be displayed on the single display screen depicting medicine concentration.

2. The computer web server of claim 1 , further comprising: conducting a multivariate pattern matching search of data related to patients other than the one or more patients.

3. The computer web server of claim 1 , wherein the particular intervention is selected from the group consisting of: administration of a medication, administration of a remedy, administration of a nutritional supplement, administration of a vitamin, exercise, physical therapy, massage, stretching, consumption of food, rest, sleep, and a modification of any of the foregoing.

4. The computer web server of claim 1 , wherein the analyzing step includes utilizing data collected from the community of patients prior to the clinical study as a baseline for comparison with the information collected after the one or more patients employ the particular intervention to treat the disease, wherein the data collected from the community of patients is directed to an intervention employed by patients to treat the disease other than the particular intervention.

5. The computer web server of claim 1 , wherein the analyzing step includes comparing the symptoms experienced by the one or more patients before the particular intervention is employed to the symptoms experienced by the one or more patients after the particular intervention is employed.

6. The web server of claim 1 , wherein the processor of the web server is further configured to cause a GUI of a client computer to generate a representation of a human body representing a plurality of human body parts generated from the analyzed information such that the represented plurality of human body parts indicate determined matching patient profiles denoting the effect of a medical condition on a body part.

Assignments (3)
SECURITY INTEREST Recorded Nov 17, 2025
From: PAULUS HOLDINGS PUBLIC LIMITED COMPANY; ALTO PHARMACY LLC; PATIENTSLIKEME LLC
To: MIDCAP FUNDING IV TRUST
Reel/Frame 072925/0813 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INVENTOR'S FIRST, SECOND AND THIRD SUFFIX ON THE COVER SHEET PREVIOUSLY RECORDED AT REEL: 036111 FRAME: 0510. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 20, 2023
From: HEYWOOD, BENJAMIN; COLE, JEFF; HEYWOOD, JAMES
To: PATIENTSLIKEME, INC.
Reel/Frame 064961/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2015
From: HEYWOOD, BENJAMIN, MR.; COLE, JEFF, MR.; HEYWOOD, JAMES, MR.
To: PATIENTSLIKEME, INC.
Reel/Frame 036111/0510 →
Continuity (7)
Continuation 13446797 · Apr 13, 2012
Continuation 12251031 · Oct 14, 2008
Continuation PCTUS2008079673 · Oct 12, 2008
Provisional Application 61070067 · Mar 20, 2008
Provisional Application 60998768 · Oct 12, 2007
Provisional Application 60998669 · Oct 12, 2007
Related Publication 20150324530A1 · Nov 12, 2015
Cited By (1)
US 12,417,825