Granted Patent
B2
US 9,433,594 · App. 14/610,417 · Granted Sep 6, 2016
Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof
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Abstract
A method of imaging a region in a subject includes administering to the subject a complex of a metal chelated to a compound, and obtaining an image of the region in the subject.
Claims (7)
1. A complex represented by any of the following formulae:
wherein n is 0 to 20, and M is a metal.
2. The complex of claim 1 , wherein the metal is a radionuclide.
3. The complex of claim 1 , where in the metal is yttrium, lutetium, gallium, or indium.
4. A pharmaceutical formulation comprising the complex of claim 1 and a pharmaceutically acceptable excipient.
5. A complex which is:
wherein n is 0 to 20, and M is yttrium, lutetium, gallium, or indium.
Assignments (4)
RELEASE OF SECURITY INTEREST
Recorded Dec 2, 2022
From: WELLS FARGO BANK, N.A.
To: PROGENICS PHARMACEUTICALS, INC.; MOLECULAR INSIGHT PHARMACEUTICALS, INC.; PSMA DEVELOPMENT COMPANY, LLC
Reel/Frame 062047/0915 →
SECURITY INTEREST
Recorded Dec 2, 2022
From: LANTHEUS MEDICAL IMAGING, INC.; MOLECULAR INSIGHT PHARMACEUTICALS, INC.; PSMA DEVELOPMENT COMPANY, LLC; PROGENICS PHARMACEUTICALS, INC.
To: CITIZENS BANK, N.A.
Reel/Frame 062047/0960 →
SECURITY AGREEMENT
Recorded Aug 19, 2020
From: PROGENICS PHARMACEUTICALS, INC.; MOLECULAR INSIGHT PHARMACEUTICALS, INC.; PSMA DEVELOPMENT COMPANY LLC
To: WELLS FARGO BANK, N.A.
Reel/Frame 053538/0666 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 11, 2016
From: BABICH, JOHN W.; ZIMMERMAN, CRAIG; JOYAL, JOHN; MARESCA, KEVIN P.; MARQUIS, JOHN; LU, GENLIANG; WANG, JIAN-CHENG; HILLIER, SHAWN
To: MOLECULAR INSIGHT PHARMACEUTICALS, INC.
Reel/Frame 039402/0884 →