IP Library Granted Patent US 9,155,731
Granted Patent B1
US 9,155,731 · App. 14/611,635 · Granted Oct 13, 2015

Methods of non-gastrointestinal endoscopic procedures using L-hyoscyamine oral formulations

Inventor: Jugal K Taneja (Tampa, FL)
A61K31/46A61K9/0053A61K45/06
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Quick Facts
Patent No.
US 9,155,731
App. No.
14/611,635
Granted
Oct 13, 2015
Kind
B1
Abstract

Methods of performing non-gastrointestinal endoscopic procedures with concomitant dosing with rapidly disintegrating oral formulations of single active ingredient L-Hyoscyamine rapidly dissolving tablets.

Claims (4)

1. A method of preventing aspiration and atelectasis in a patient having head and neck cancer, said method including the step of administering an oral formulation of L-Hyoscyamine, said method including the further step of head and neck endoscopy combined with an at least one procedure of fine needle injection into a head and neck cancer lesion/tumor.

2. The method of claim 1 whereby said method further enhancing and unobstructing head and neck cancer endoscopic visualization, said method including the step of administering said oral formulation of L-Hyoscyamine as an antispasmodic agent to relax and flatten any bulges or folds in or around a suspected head and neck cancer lesion so that said head and neck cancer lesion can be treated concomitantly with a head and neck cancer endoscopic procedure.

3. The method of claim 1 whereby said oral formulation of L-Hyoscyamine is at least 0.125 mg and said at least one procedure of fine needle injection into a head and neck cancer lesion/tumor is selected from intratumoral chemotherapy and tumor ablation, said method further including the drying of secretions within the head and neck, said method providing improved direct visualization and advancement with a head and neck endoscope by alleviating obstruction in proximity to a head and neck cancer lesion, said method further reducing/preventing reflex airway constriction, and said method further providing bronchodilation.

4. A method of preventing aspiration and atelectasis in a patient having head and neck cancer, said method including the step of administering an oral formulation of L-Hyoscyamine, said method including the further step of head and neck endoscopy combined with an at least one procedure of fine needle injection into a head and neck cancer lesion/tumor, said method further enhancing and unobstructing head and neck cancer endoscopic visualization, said method including the step of administering said oral formulation of L-Hyoscyamine as an antispasmodic agent to relax and flatten any bulges or folds in or around a suspected head and neck cancer lesion so that said head and neck cancer lesion can be treated concomitantly with a head and neck cancer endoscopic procedure, said oral formulation of L-Hyoscyamine being at least 0.125 mg and said at least one procedure of fine needle injection into a head and neck cancer lesion/tumor is selected from intratumoral chemotherapy and tumor ablation, said method further including the drying of secretions within the head and neck, said method providing improved direct visualization and advancement with a head and neck endoscope by alleviating obstruction in proximity to a head and neck cancer lesion, said method further reducing/preventing reflex airway constriction, and said method further providing bronchodilation.

Assignments (7)
SECURITY INTEREST Recorded Feb 20, 2025
From: BELCHER PHARMACEUTICALS, LLC
To: TRUIST BANK, AS ADMINISTRATIVE AGENT
Reel/Frame 070279/0798 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY COLLATERAL Recorded Sep 16, 2021
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: BELCHER PHARMACEUTICALS, LLC
Reel/Frame 057525/0648 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Sep 14, 2021
From: BELCHER PHARMACEUTICALS, LLC
To: TRUIST BANK
Reel/Frame 057499/0790 →
RELEASE OF SECURITY INTEREST Recorded Sep 11, 2020
From: THE NORTHERN TRUST COMPANY
To: BELCHER PHARMACEUTICALS, LLC
Reel/Frame 053748/0507 →
SECURITY INTEREST Recorded Sep 10, 2020
From: BELCHER PHARMACEUTICALS, LLC
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 053731/0843 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2017
From: TANEJA, JUGAL K.
To: BELCHER PHARMACEUTICALS, LLC
Reel/Frame 043375/0234 →
SECURITY INTEREST Recorded Aug 23, 2017
From: BELCHER PHARMACEUTICALS, LLC
To: THE NORTHERN TRUST COMPANY
Reel/Frame 043375/0478 →
Continuity (2)
Continuation In Part 13965819 · Aug 13, 2013
Continuation In Part 12931784 · Feb 10, 2011