IP Library Granted Patent US 9,351,769
Granted Patent B2
US 9,351,769 · App. 14/616,099 · Granted May 31, 2016

Method of treating spinal internal disk derangement

Inventors: Neville Alleyne (La Jolla, CA); Stuart Young (Del Mar, CA)
Assignee: SpineOvations, Inc.
A61B17/7061A61B17/7094A61F2/442A61F2/4455A61F2002/3008A61F2002/30062A61F2002/30242A61F2002/30754A61F2002/444A61F2002/4435A61F2230/0071A61F2250/0098A61F2310/00365
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Quick Facts
Patent No.
US 9,351,769
App. No.
14/616,099
Granted
May 31, 2016
Kind
B2
Abstract

A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.

Claims (16)

1. A method of treating a spinal disk comprising injecting a biocompatible agent into an interior portion of the spinal disk, wherein the biocompatible agent comprises a plurality of microparticles, the plurality of microparticles having a diameter in the range of 5 to 500 microns, wherein the plurality of microparticles are inserted into the spinal disk as loose microparticles and remain therein as loose microparticles.

2. The method of claim 1 , wherein injecting a biocompatible agent into an interior portion of the spinal disk comprises injecting the biocompatible agent into a center of the spinal disk.

3. The method of claim 1 , wherein injecting a biocompatible agent into an interior portion of the spinal disk comprises injecting the biocompatible agent into a nucleus pulposus of the spinal disk.

4. The method of claim 1 , further comprising at least one of sealing a defect in the spinal disk, increasing a pressure of the spinal disk, increasing a height of the spinal disk, improving stability of the spinal disk, and improving structural integrity of the spinal disk.

5. The method of claim 1 , wherein the plurality of microparticles are suspended in a solution comprising collagen.

6. The method of claim 1 , wherein the biocompatible agent comprises at least one of water, saline, a tenside, radiopaque dye, and a chromophobe.

7. The method of claim 1 , wherein the plurality of microparticles comprise a histocompatible solid.

8. The method of claim 1 , wherein the plurality of microparticles comprise an inert histocompatible polymer.

9. The method of claim 1 , wherein the plurality of microparticles microparticles comprise one or more of poly methacrylate, polymethylmethacrylate (PMMA), a cured polymer, a fully polymerized polymer, and glass.

10. The method of claim 1 , further comprising viewing the spinal disk through a scope.

11. The method of claim 1 , wherein injecting the biocompatible agent comprises delivering about 0.5 to 1.5 cubic centimeters of the biocompatible agent into a center of the spinal disk.

12. The method of claim 1 , wherein injecting the biocompatible agent comprises inserting a syringe into a center of the spinal disk.

13. The method of claim 1 , wherein injecting the biocompatible agent occurs during at least one of a discography, laminotomy, laminectomy, hemilaminotomy, and hemilaminectomy, and open procedure.

14. The method of claim 1 , further comprising displacing a nucleus pulposus of the spinal disk from a site of implantation of the biocompatible agent, the displacement of the nucleus pulposus in a direction toward an annulus fibrosis defect of the spinal disk.

15. The method of claim 1 , further comprising introducing the biocompatible agent into a nucleus pulposus of the spinal disk in a direct or proximate vicinity of an annulus fibrosis defect of the spinal disk.

16. A method of sealing an annulus fibrosis defect in a spinal disk comprising injecting a biocompatible agent into a nucleus pulposus of the spinal disk in a direct or proximate vicinity of the annulus fibrosis defect, wherein the biocompatible agent comprises a plurality of microparticles, the plurality of microparticles having a diameter in the range of 5 to 500 microns, the plurality of microparticles inserted into the spinal disk as loose microparticles and remaining therein as loose microparticles, wherein the biocompatible agent causes a seal to be formed in and around the annular fibrosis defect.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2023
From: SPREZZATURA INNOVATIONS, LLC
To: 33 MEDICAL, INC.
Reel/Frame 064676/0869 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2023
From: SPINEOVATIONS, INC.
To: SPREZZATURA INNOVATIONS, LLC
Reel/Frame 063035/0928 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 26, 2016
From: ALLEYNE, NEVILLE; YOUNG, STUART
To: SPINEOVATIONS, INC.
Reel/Frame 038383/0889 →
Continuity (4)
Continuation 13790259 · Mar 8, 2013
Continuation 11215809 · Aug 30, 2005
Provisional Application 60605709 · Aug 30, 2004
Related Publication 20150238234A1 · Aug 27, 2015