Nasal delivery
View Patent ↗A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece for fitting to a nostril of a subject, wherein the nosepiece comprises a tip element which includes a delivery aperture from which substance is in use delivered into the nasal cavity, and the tip element is at least in part tapered such as to be inclined to a longitudinal axis of the nosepiece, with the delivery aperture extending both laterally across the tip element and along a longitudinal extent of the tip element; a nozzle through which substance is in use delivered, preferably substantially axially to a longitudinal axis of the nosepiece, to the respective nasal cavity; and a delivery unit for delivering substance through the nozzle of the nosepiece.
1. A method of fitting a nasal delivery device to a nostril of a subject, the method comprising:
inserting a nosepiece of the nasal delivery device into one of the nostrils of the subject, with the nasal delivery device having a first alignment;
twisting the nosepiece in the nostril so as to rotate the nasal delivery device to have a second alignment which is different from the first alignment and in which a mouthpiece of the nasal delivery device is aligned with a mouth of the subject;
sealing a nare of the nostril against the nosepiece; and
causing the subject to exhale through the mouthpiece.
2. The method of claim 1 , further comprising:
applying a grip-enhancing agent to an exterior surface of a nose of the subject.
3. The method of claim 1 , wherein the nosepiece comprises a tip element.
4. The method of claim 3 , wherein the tip element is substantially elliptical.
5. The method of claim 3 , wherein the tip element is substantially rectangular.
6. The method of claim 3 , wherein the tip element comprises a delivery aperture.
7. The method of claim 3 , wherein the tip element is tapered.
8. The method of claim 1 , wherein the nasal delivery device comprises a substance supply unit and a nose gripping member.
9. The method of claim 8 , wherein the nose gripping member is tethered to a body of the nasal delivery device.
10. The method of claim 8 , wherein the nose gripping member comprises a gripping element which is configured to be fixed to a nose of the subject.
11. The method of claim 1 , further comprising;
pressing a finger against the skin of the nose so as to press the nare of the nostril against the nosepiece.
12. The method of claim 1 , further comprising:
pulling the nare of the nostril over the nosepiece.
13. The method of claim 12 , wherein the pulling is done by a finger.