IP Library Granted Patent US 9,743,853
Granted Patent B2
US 9,743,853 · App. 14/622,585 · Granted Aug 29, 2017

Electromyography system

Inventors: Brian S. Kelleher (Ramona, CA); James F. Marino (La Jolla, CA); Corbett W. Stone (San Diego, CA); Robin H. Vaughn; Jeffrey H. Owen (Monkton, MD)
Assignee: NuVasive, Inc.
A61B5/04001A61B5/0488A61B5/4836A61B5/4893A61B17/00234A61B5/0492A61B2017/00022A61B2017/00039A61N1/08
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Quick Facts
Patent No.
US 9,743,853
App. No.
14/622,585
Granted
Aug 29, 2017
Kind
B2
Abstract

Methods for determining structural integrity of a bone within the spine of a patient, the bone having a first aspect and a second aspect, wherein the second aspect separated from the first aspect by a width and located adjacent to a spinal nerve. The methods involve (a) applying an electrical stimulus to the first aspect of the bone; (b) electrically monitoring a muscle myotome associated with the spinal nerve to detect if an onset neuro-muscular response occurs in response to the application of the electrical stimulus to the first aspect of the bone; (c) automatically increasing the magnitude of the electrical stimulus to until the onset neuro-muscular response is detected; and (d) communicating to a user via at least one of visual and audible information representing the magnitude of the electrical stimulus which caused the onset neuro-muscular response.

Claims (32)

1. A method of performing a spinal surgical procedure, the method comprising:

advancing a stimulation cannula including a stimulation electrode at a distal end of the stimulation cannula along an access path toward an operative site in the region of a patient's lumbar spine;

using the stimulation cannula to perform nerve detection of a spinal nerve while the stimulation cannula is advanced in the access path toward the operative site in the region of the lumbar spine by stimulating the stimulation electrode at the distal end of the stimulation cannula and monitoring an electrical current level determined after a neuro-muscular onset response is detected via one or more return electrodes positioned on the patient's leg,

using an elongated probe to perform nerve detection of one or more spinal nerves while the elongated probe is advanced toward the operative site in the region of the lumbar spine by stimulating a second stimulation electrode at a distal end of the elongated probe and monitoring for neuro-muscular response via one or more of the plurality of return electrodes on the patient's leg; and

positioning the elongated probe in the stimulation cannula.

2. The method of claim 1 , wherein nerve detection is continuously repeated as the stimulation cannula is physically advanced into the patient by a surgeon such that the surgeon is warned when the stimulation cannula closely approaches the spinal nerve.

3. The method of claim 1 , wherein the spinal nerve is one of a plurality of spinal nerves exiting from successive vertebrae, the method further comprising:

performing nerve detection of the plurality of spinal nerves exiting from successive vertebrae as the stimulation cannula is advanced toward the operative site in the region of the lumbar spine by stimulating the stimulation electrode at the distal end of the stimulation cannula and monitoring for neuro-muscular response via one or more of the plurality of return electrodes.

4. The method of claim 1 , and further comprising:

detecting neuro-muscular responses at a plurality of spaced apart myotome locations corresponding to each of the plurality of spinal nerves.

5. The method of claim 1 , and further comprising:

measuring current intensity level at which the neuro-muscular response is detected by the one or more of the plurality of return electrodes.

6. The method of claim 1 , wherein the spinal nerve is a spinal nerve root.

7. The method of claim 1 , wherein the spinal nerve is a nerve in the cauda equine.

8. The method of claim 1 , and further comprising:

repeatedly performing nerve detection while current intensity level of a stimulation pulse emitted by the stimulation electrode is varied over time.

9. The method of claim 1 , and further comprising:

repeatedly performing nerve detection while current intensity level of a stimulation pulse emitted by the stimulation electrode is varied incrementally.

10. The method of claim 1 , and further comprising:

visually displaying an intensity level of a neuro-muscular response onset value for the spinal nerve on a display of a nerve monitoring system.

11. The method of claim 1 , wherein the stimulation cannula is advanced in the patient by a surgeon in a minimally invasive approach such that the stimulation cannula is advanced without causing any nerve damage.

12. The method of claim 1 , wherein the stimulation cannula is part of a nerve detection system operated by a surgeon to provide nerve detection warnings to alert the surgeon operating the nerve detection system that the spinal nerve is in close proximity to the stimulation electrode.

13. The method of claim 1 , wherein using the elongated probe to perform nerve detection is performed after using the stimulation cannula to perform nerve detection.

14. A method of performing a spinal surgical procedure, the method comprising:

advancing a stimulation cannula including a stimulation electrode at a distal end of the stimulation cannula along an access path toward an operative site in the region of a patient's lumbar spine;

using the stimulation cannula to perform nerve detection of a spinal nerve while the stimulation cannula is advanced in the access path toward the operative site in the region of the lumbar spine by stimulating the stimulation electrode at the distal end of the stimulation cannula and monitoring an electrical current level determined after a neuro-muscular onset response is detected via one or more return electrodes positioned on the patient's leg,

wherein the stimulation cannula is part of a nerve detection system operated by a surgeon to provide nerve detection warnings to alert the surgeon operating the nerve detection system that the spinal nerve is in close proximity to the stimulation electrode, wherein the spinal nerve is one of a plurality of spinal nerves exiting from successive vertebrae, the method further comprising:

positioning an elongated probe in the stimulation cannula;

using the stimulation cannula to perform nerve detection of the plurality of spinal nerves exiting from successive vertebrae while the stimulation cannula is advanced toward the operative site in the region of the lumbar spine by stimulating the stimulation electrode at the distal end of the stimulation cannula and monitoring for neuro-muscular response via one or more of the plurality of return electrodes;

using the elongated probe to perform nerve detection of the plurality of spinal nerves while the elongated probe is advanced toward the operative site in the region of the lumbar spine by stimulating a second stimulation electrode at a distal end of the elongated probe and monitoring for neuro-muscular response via one or more of the plurality of return electrodes on the patient's leg;

detecting neuro-muscular responses at a plurality of spaced apart myotome locations corresponding to each of the plurality of spinal nerves, and

positioning the elongated probe in the stimulation cannula so as to extend into the stimulation cannula.

Assignments (4)
SECURITY INTEREST Recorded Feb 28, 2020
From: NUVASIVE, INC.; NUVASIVE CLINICAL SERVICES MONITORING, INC.; NUVASIVE CLINICAL SERVICES, INC.; NUVASIVE SPECIALIZED ORTHOPEDICS, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 052918/0595 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded May 17, 2017
From: NUVASIVE, INC.; BIOTRONIC NATIONAL, LLC; NUVASIVE CLINICAL SERVICES MONITORING, INC.; NUVASIVE CLINICAL SERVICES, INC.; NUVASIVE SPECIALIZED ORTHOPEDICS, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 042490/0236 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Nov 16, 2016
From: NUVASIVE, INC.; IMPULSE MONITORING, INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 040634/0404 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 25, 2015
From: KELLEHER, BRIAN S.; MARINO, JAMES F.; STONE, CORBETT W.; VAUGHN, ROBIN H.; OWENS, JEFFREY H.
To: NUVASIVE, INC.
Reel/Frame 035031/0647 →
Continuity (7)
Continuation 13726110 · Dec 22, 2012
Continuation 13196784 · Aug 2, 2011
Continuation 11982238 · Oct 31, 2007
Continuation 10830189 · Apr 21, 2004
Division 09722070 · Nov 24, 2000
Provisional Application 60167416 · Nov 24, 1999
Related Publication 20150157227A1 · Jun 11, 2015