IP Library Granted Patent US 9,662,312
Granted Patent B2
US 9,662,312 · App. 14/631,768 · Granted May 30, 2017

Method for treating glomerulosclerosis

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Quick Facts
Patent No.
US 9,662,312
App. No.
14/631,768
Granted
May 30, 2017
Kind
B2
Abstract

Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are disclosed for treating diseases.

Claims (5)

1. A method of treating glomerulosclerosis comprising administering to a subject in need thereof an effective amount of a compound of Formula I:

or a pharmaceutically acceptable salt thereof, wherein the amount of the compound of Formula I, or pharmaceutically acceptable salt thereof, administered to the subject is 200 mg/day, 400 mg/day, or 800 mg/day.

2. The method according to claim 1 , wherein the amount of the compound of Formula I, or pharmaceutically acceptable salt thereof, administered to the subject is 200 mg/day.

3. The method according to claim 1 , wherein the amount of the compound of Formula I, or pharmaceutically acceptable salt thereof, administered to the subject is 400 mg/day.

4. The method according to claim 1 , wherein the amount of the compound of Formula I, or pharmaceutically acceptable salt, administered to the subject is 800 mg/day.

Assignments (2)
SECURITY INTEREST Recorded Oct 18, 2023
From: CYDEX PHARMACEUTICALS, INC.; LIGAND PHARMACEUTICALS INCORPORATED; METABASIS THERAPEUTICS, INC.; PFENEX INC.
To: CITIBANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 065271/0025 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2016
From: ZHANG, JINKUN; DZIEWANOWSKA, ZOFIA E.; BELDER, RENE; HENDERSON, IAN; BOGARDUS, JOSEPH B.; ZHANG, ZHAOYING
To: LIGAND PHARMACEUTICALS INC.
Reel/Frame 039168/0520 →