Endovascular plasma treatment device and method of use
View Patent ↗A device and method for treating a hollow anatomical structure using matter in a plasma state. Device includes a tubular delivery device comprising a tubular body, a hub, and a distal end, wherein the tubular body device having a longitudinal fluid delivery channel and an exit port near the distal end. Device also contains a container having pre-plasma matter being operatively coupled to the hub, at least one energy-emitting element operatively coupled near the distal end of the tubular delivery device. The energy-emitting element is operatively connected to energy source.
1. An endoluminal treatment method comprising:
accessing an anatomical lumen;
inserting into an anatomical lumen a catheter having at least one energy emitting element near the distal end of the catheter and a catheter lumen;
activating the energy emitting element to create plasma wherein the plasma causes shrinkage of the anatomical lumen by altering a cellular component of a cellular lining of the anatomical lumen to induce non-thermal cell death.
2. The method of claim 1 , wherein plasma is created from pre-plasma matter by activating the energy emitting element.
3. The method of claim 2 , wherein the pre-plasma is in a fluid state.
4. The method of claim 3 , wherein the pre-plasma comprises a saline.
5. The method of claim 1 , wherein the step of inserting includes the energy emitting element comprising an optical fiber.
6. The method of claim 1 , wherein the step of inserting includes the energy emitting element comprising an electrode.
7. The method of claim 6 , wherein the electrode further comprises a radiofrequency electrode.
8. The method of claim 6 , wherein the electrode further comprises an electroporation electrode.
9. The method of claim 6 , wherein the electrode further comprises a microwave antenna.
10. The endoluminal treatment method of claim 1 , wherein the plasma causing shrinkage of the anatomical lumen comprises low-level thermal plasma.
11. An endoluminal treatment method comprising:
accessing a varicose vein;
inserting into a varicose vein a catheter having at least one energy emitting element and a catheter lumen;
activating the at least one energy emitting element to create plasma wherein the plasma causes shrinkage of the varicose vein by altering a cellular component of a cellular lining of the varicose vein to induce non-thermal cell death.
12. The method of claim 11 , wherein plasma is created from pre-plasma matter by activating the energy emitting element.
13. The method of claim 12 , wherein the pre-plasma is in a fluid state.
14. The method of claim 13 , wherein the pre-plasma comprises a saline.
15. The method of claim 11 , wherein the step of inserting includes the energy emitting element comprising an optical fiber.
16. The method of claim 11 , wherein the step of inserting includes the energy emitting element comprising an electrode.
17. The method of claim 16 , wherein the electrode further comprises a radiofrequency electrode.
18. The method of claim 16 , wherein the electrode further comprises an electroporation electrode.
19. The method of claim 16 , wherein the electrode further comprises a microwave antenna.
20. The endoluminal treatment method of claim 11 , wherein the plasma causing shrinkage of the anatomical lumen comprises low-level thermal plasma.
21. An endoluminal treatment device comprising:
an energy generator comprising a device capable of generating an energy field to excite pre-plasma matter sufficiently to convert the matter to plasma, the plasma altering a cellular component of a cellular lining of an anatomical lumen to induce non-thermal cell death;
a delivery catheter; and
a connection between the energy generator and delivery catheter.