IP Library Granted Patent US 11,118,172
Granted Patent B2
US 11,118,172 · App. 14/632,941 · Granted Sep 14, 2021

System and method for using electromagnetic radiation to influence cellular structures

Inventors: Robert Edward Grant (Laguna Beach, CA); Todd Mirzai (Honolulu, HI); Matthew T. Case (Laguna Hills, CA)
Assignee: STRATHSPEY CROWN HOLDINGS, LLC
C12N13/00A61B5/0036A61B5/053A61B18/18A61N1/06A61N5/00A61N7/00A61B5/0066A61B5/055A61B6/03A61B8/08A61B2017/00154A61B2017/00194A61B2018/00636A61B2018/00875A61B2090/374A61B2090/378A61B2090/3735A61B2090/3762
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Quick Facts
Patent No.
US 11,118,172
App. No.
14/632,941
Granted
Sep 14, 2021
Kind
B2
Abstract

A system and method for the present invention requires use of a generator, in combination with a radiation unit, to radiate electromagnetic waveform energy onto a target tissue (i.e. a cellular structure). During radiation of the target tissue in accordance with a predetermined titration-like protocol, the influence of the waveform energy on the cellular structure is periodically monitored. The protocol is stopped when the cellular structure has been transformed or morphed into a desired phenotype.

Claims (31)

1. A method to epigenetically influence a cancerous cell in a target tissue comprising:

determining a resonant frequency of the cancerous cell;

defining a desired phenotype for the cancerous cell;

generating waveform energy at an octave of the resonant frequency;

directing the waveform energy onto the target tissue to epigenetically influence the cancerous cell; and

using a sensor to monitor a phenotypic response of the cancerous cell to the waveform energy to determine whether the cancerous cell has produced the desired phenotype;

wherein the sensor is configured to monitor the phenotypic response of the cancerous cell via a bioelectrical impedance analysis, and

wherein the desired phenotype is a cancer-free cellular structure.

2. The method as recited in claim 1 further comprising:

tuning the waveform energy to select a wavelength λ that corresponds to the octave of the resonant frequency;

adjusting a peak value of amplitudes of the waveform energy to a selected intensity level v;

providing a predetermined time duration t d for activation of the generating step; and

selectively moving an operational fluence along a predefined pathway through the target tissue.

3. The method as recited in claim 2 , wherein the waveform energy is continuous during the predetermined duration t d .

4. The method as recited in claim 2 wherein the tuning step is accomplished by selecting the wavelength λ of the waveform energy for transit through tissue surrounding the target tissue, to the target tissue at a penetration depth.

5. The method as recited in claim 2 wherein the waveform energy is pulsed during the generating step, with each waveform energy pulse having radiation of the predetermined time duration t d within a predetermined time interval t i between successive beginnings of respective waveform energy pulses.

6. The method as recited in claim 1 wherein the generating step further comprises exciting a plasma with the waveform energy in the form of electromagnetic radiation to create a longitudinal electromagnetic wave, wherein the plasma is confined in a plasma antenna.

7. The method as recited in claim 1 further comprising a step of imaging the target tissue to create images of the target tissue for use during the directing step.

8. The method as recited in claim 7 wherein the imaging step is accomplished using a technique selected from a group consisting of Optical Coherence Tomography (OCT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Computerized Axial Tomography (CAT), or Ultrasound.

9. The method as recited in claim 7 wherein the waveform energy is at least one of an X-ray and a gamma ray.

10. A method for epigenetically influencing a cancerous cellular structure in a target tissue comprising steps of:

defining a desired phenotype for the cancerous cellular structure in the target tissue, wherein the cancerous cellular structure has a fundamental frequency, and the desired phenotype is a cancer-free cellular structure;

radiating the target tissue with waveform energy at the fundamental frequency via a predetermined protocol to result in a phenotypic response of the cancerous cellular structure;

monitoring the phenotypic response of the cancerous cellular structure in the target tissue by a sensor via a bioelectrical impedance analysis; and

terminating the predetermined protocol when the phenotypic response corresponds with the desired phenotype.

11. The method as recited in claim 10 wherein the predetermined protocol further comprises:

tuning the radiation to a wavelength λ that corresponds to the fundamental frequency;

adjusting a peak value of amplitudes of the radiation to a volume intensity level v; and

providing the time duration t d for activation of the generating step.

12. The method as recited in claim 10 wherein the waveform energy is electromagnetic radiation having a functional relationship with the fundamental frequency, and wherein the electromagnetic radiation is established by an octave evaluation.

13. The method as recited in claim 10 , wherein the target tissue is selected from a group consisting of in vivo tissue and in vitro tissue.

Assignments (2)
CHANGE OF NAME Recorded Apr 25, 2023
From: STRATHSPEY CROWN, LLC
To: CROWN HOLDINGS, LLC
Reel/Frame 063439/0244 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 16, 2015
From: GRANT, ROBERT EDWARD; MIRZAI, TODD; CASE, MATTHEW T.
To: STRATHSPEY CROWN HOLDINGS, LLC
Reel/Frame 035426/0896 →
Continuity (2)
Continuation In Part 14488101 · Sep 16, 2014
Related Publication 20160074669A1 · Mar 17, 2016