Automated sequential injection and blood draw
View Patent ↗Devices are provided to automatically inject drugs or other payloads into or beneath skin. These devices include an injector configured to drive a hollow needle into the skin and subsequently to deliver the payload through the hollow needle. Applied suction acts to draw blood from the puncture formed in the skin through the hollow needle, into the device, and to a sensor, blood storage element, or other payload. In some examples, the blood is drawn through the hollow needle when the hollow needle is penetrating the skin. In some examples, these devices are additionally configured to retract the hollow needle from the skin and/or to perform some other functions. These devices can be wearable and configured to automatically access blood or deliver a payload into skin, for example, to operate at one or more points in time while a wearer of a device is sleeping.
1. A system comprising:
a housing;
a seal disposed on a surface of the housing;
a first chamber disposed within the housing, wherein the first chamber contains a sealant layer;
a hollow needle disposed in the first chamber and configured to pierce the sealant layer, wherein the hollow needle comprises a first channel;
a reservoir, wherein the reservoir contains a payload;
an injector, wherein the injector is operable to drive the hollow needle through the seal to form a hole in the seal and thereafter into skin to form a puncture in the skin, such that the payload is delivered from the reservoir into the skin via the first channel;
a second chamber disposed within the housing;
a second channel coupled to the second chamber, wherein the second channel is formed by the seal and the housing;
a suction source configured to provide suction, wherein the suction provided by the suction source is configured to draw blood from the puncture formed in the skin into the second chamber via the hole formed in the seal and the second channel;
a sensor; and
a controller, wherein the controller is configured to perform controller functions including:
operating the sensor to detect information about an environment of the system;
determining that a specified condition has occurred based on the information about the environment of the system detected using the sensor; and
responsive to determining that the specified condition has occurred, operating the injector to drive the hollow needle through the seal and into the skin to deliver the payload into the skin via the first channel.
2. The system of claim 1 , wherein the injector comprises:
a piston disposed in the first chamber, wherein the hollow needle is coupled to the piston, wherein the piston comprises the reservoir, and wherein the piston is configured to slidably move within the first chamber; and
a propellant, wherein the propellant is configured to slidably move the piston within the first chamber to drive the hollow needle through the seal and into skin.
3. The system of claim 1 , wherein the seal comprises a concave depression, wherein the injector is configured to drive the hollow needle into skin proximate the concave depression, and wherein the suction provided by the suction source is configured to suction the skin into the concave depression.
4. The system of claim 1 , wherein the sensor is disposed in the second channel, and wherein the sensor is configured to detect a property of blood to which the sensor is exposed.
5. The system of claim 1 , wherein the payload contained by the reservoir comprises heparin.
6. The system of claim 1 , wherein determining that a specified condition has occurred comprises determining that a specified point in time has been reached.
7. The system of claim 1 , wherein the suction source comprises an evacuated volume in the second chamber.
8. The system of claim 1 , further comprising a spring disposed within the first chamber, wherein the spring is configured to retract the hollow needle from the skin.