IP Library › Granted Patent US 10,456,474
Granted Patent B2
US 10,456,474 · App. 14/635,648 · Granted Oct 29, 2019

Cyclosporin compositions

Inventors: James N. Chang (Newport Beach, CA); Orest Olejnik (Coto de Caza, CA); Bruce A. Firestone (Irvine, CA)
Assignee: Saint Regis Mohawk Tribe
A61K47/44A61K9/0048A61K9/107A61K38/13Y10S514/912Y10S514/975
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Quick Facts
Patent No.
US 10,456,474
App. No.
14/635,648
Granted
Oct 29, 2019
Kind
B2
Abstract

A composition comprising from about 0.001% to about 0.4% cyclosporin A, a surfactant, and an oil having a specific gravity from 0.8 to 0.95 is disclosed herein.

Claims (11)

1. A method of treating keratoconjunctivitis sicca, the method comprising administering a composition comprising about 0.001% cyclosporin A, a surfactant, and an oil selected from the group consisting of almond oil, corn oil, arachis oil, cottonseed oil, safflower oil, rosemary oil, peanut oil, peppermint oil, sunflower oil, and eucalyptus oil to a patient in need thereof, wherein said composition is an ophthalmically acceptable emulsion.

2. The method of claim 1 comprising almond oil.

3. The method of claim 1 comprising corn oil.

4. The method of claim 1 comprising arachis oil.

5. The method of claim 1 comprising cottonseed oil.

6. The method of claim 1 comprising safflower oil.

7. The method of claim 1 comprising rosemary oil.

8. The method of claim 1 comprising peanut oil.

9. The method of claim 1 comprising peppermint oil.

10. The method of claim 1 comprising sunflower oil.

11. The method of claim 1 comprising eucalyptus oil.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2017
From: ALLERGAN, INC.
To: SAINT REGIS MOHAWK TRIBE
Reel/Frame 043830/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2015
From: CHANG, JAMES N.; OLEJNIK, OREST; FIRESTONE, BRUCE A.
To: ALLERGAN, INC.
Reel/Frame 035073/0601 →