Granted Patent
B2
US 9,957,393 · App. 14/672,944 · Granted May 1, 2018
Monoazo dyes with cyclic amine as fluorescence quenchers
Inventors:
Zaiguo Li (Little Neck, NY); Praveen Pande (Holbrook, NY); Natarajan Raju (Kendall Park, NY)
Assignee:
Enzo Biochem, Inc.
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Abstract
The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.
Claims (3)
1. A compound selected from the group consisting of
2. The compound of claim 1 having the structure
3. The compound of claim 1 having the structure
Assignments (3)
RELEASE OF SECURITY INTEREST
Recorded Jul 24, 2023
From: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
To: ENZO BIOCHEM, INC.; ENZO CLINICAL LABS, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP; ENZO LIFE SCIENCES, INC.
Reel/Frame 064369/0031 →
SECURITY INTEREST
Recorded Apr 3, 2023
From: ENZO LIFE SCIENCES, INC.; ENZO CLINICAL LABS, INC.; ENZO BIOCHEM, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP
To: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
Reel/Frame 063239/0103 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 31, 2015
From: LI, ZAIGUO; PANDE, PRAVEEN; RAJU, NATARAJAN
To: ENZO BIOCHEM, INC.
Reel/Frame 035345/0940 →
Continuity (1)