IP Library › Patent Application 14677333
Patent Application
App. No. 14/677,333

Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders

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Quick Facts
Patent No.
US None
App. No.
14/677,333
Abstract

Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.

Claims (6)

1 . A method for the synthesis of a compound of Formula XXIV:

comprising the step of reacting a compound of Formula XXIII:

with an aldehyde or ketone of formula; C(O)—C(R 101 )(R 103 ).

2 . The process according to claim 1 , wherein said aldehyde is paraformaldehyde.

3 . The process according to claim 1 further comprising the step of reacting said compound of Formula XXIII with an acid anhydride.

4 . The process according to claim 3 , wherein said acid anhydride is selected from acetic anhydride, butyric anhydride, hexanoic anhydride, octanoic anhydride, decanoic anhydride, dodecanoic anhydride, lauric anhydride, and palmitic anhydride.

Assignments (1)
SECURITY INTEREST Recorded May 19, 2015
From: ALKERMES PHARMA IRELAND LIMITED
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 035674/0871 →