Fenestrated bone graft
View Patent ↗The present invention relates to a fenestrated bone graft and a method of preparing cortical bone in thin strips then fully demineralizing it to give it formed flexibility and then creating fenestrations in the cortical bone in a fashion similar to but not identical to skin grafts.
1. A fenestrated cortical bone graft comprises:
a textured and flexible allograft bone structure, the allograft bone structure being made from a single piece of long cortical bone of 8 cm length or greater from a rib or 10 cm length or greater from a tibia, the rib treated in 1N-HCL for 1 to 3 hours whereas the tibia is treated in 1N-HCL for 4 to 6 hours to texture the cortical bone and make pliable or flexible, the cortical bone being cut along a length of the bone and laid flat in a flat sheet, the structure having an outer surface and an inner surface, the structure being fenestrated along a length of the bone structure with a plurality of cut slits sized to uniformly extend through from the outer surface to the inner surface to form a plurality of open passages when the bone structure is stretched, the fenestrated cortical bone graft being freeze-dried and packaged sterilely for clinical use, the freeze-dried fenestrated cortical bone graft being hydrated and reconstituted in saline with or without antibiotics or lactated ringers with or without antibiotics for clinical use to resume the pliable or flexible condition of the freeze-dried fenestrated cortical bone graft, the open passages being bounded by an interconnected network of bone struts defined by pairs of adjacent slits, each bone strut having a width of 0.8 to 1.2 mm that doubles at connective portions, the bone struts in combination with the slits giving the hydrated and reconstituted fenestrated cortical bone graft stretchability and flexibility wherein the allograft bone structure is formed as the flat sheet, the flat sheet of the allograft bone structure is made pliable and conformable by the treatment in 1N-HCL which also demineralizes the bone allowing the flat sheet to be formed into different shapes, wherein the bone allograft structure has a thickness of 0.2 mm to 1 mm as measured from the inner surface to the outer surface and wherein the structure when stretched has the slits opened, the slits being sized in length allows the open passages to be of an oblong shape in the range of 0.2 mm to 5 mm when the sheet is stretched and the plurality of slits are configured by cutting through the flat sheet using a bone cutter with cutting blades, cutting fenestrations in the flat sheet which open when the flat sheet is stretched, wherein each slit is of a length prior to stretching and the openness of each of the slits varies dependent on the amount of stretch on the fenestrated cortical bone graft.