IP Library › Granted Patent US 9,381,181
Granted Patent B2
US 9,381,181 · App. 14/684,100 · Granted Jul 5, 2016

Treatment of NAFLD and NASH

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,381,181
App. No.
14/684,100
Granted
Jul 5, 2016
Kind
B2
Abstract

Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.

Claims (6)

1. A method of treating a disease that is non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) by orally administering a therapeutically effective amount of (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)-propyl)thio)-2-methylphenoxy)acetic acid L -lysine dihydrate salt (MBX-8025 L -lysine dihydrate salt).

2. The method of claim 1 where the dose of MBX-8025 L -lysine dihydrate salt (when calculated as the free acid) is 20-200 mg/day.

3. The method of claim 2 where the dose of MBX-8025 L -lysine dihydrate salt (when calculated as the free acid) is 50-100 mg/day.

4. The method of claim 1 where the MBX-8025 L -lysine dihydrate salt is administered once/day.

5. The method of claim 1 where the disease is NAFLD.

6. The method of claim 1 where the disease is NASH.

Assignments (2)
RELEASE OF SECURITY INTEREST Recorded Oct 3, 2024
From: ABW CYCLOPS SPV LP
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 069833/0155 →
NUNC PRO TUNC ASSIGNMENT Recorded Apr 12, 2016
From: CHOI, YUN-JUNG; MARTIN, ROBERT; MCWHERTER, CHARLES; WANG, XUEYAN; KARPF, DAVID; ROBERTS, BRIAN
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 038252/0464 →