System and method for DNA sequencing and blood chemistry analysis
A DNA sequencing and blood chemistry analysis device is provided including one or more sensor chips and one or more sample wells, wherein each sample well is configured to form a seal with one of the sensors. The one or more sensor chips may comprise Graphene transistors, and each transistor having an associated sequencing probe. The sensor chips interact with a biological sample introduced into the sample well, wherein changes in the current, transconductance, and resistance of the Graphene transistors are indicative of a DNA binding process. Based on the associated sequencing probes, the DNA sequence present in a biological sample can be identified.
1. A system for biological sample analysis comprising:
a biological sample sensor comprising a plurality of transistors, wherein at least one transistor comprises a scattering site;
at least one transistor comprises sp 2 hybridized Carbon in the form of Graphene and each scattering site comprises sp 3 hybridized Carbon, the sp 3 hybridized Carbon being covalently bonded to a sequencing probe, such that if the sequencing probe detects a complimentary DNA sequence while voltage is applied to the transistor, the electrical properties of the transistor will change;
a sample well having a bottom portion, wherein the sample well is in fluidic communication with the biological sample sensor; and
a computing module, wherein the computing module is configured to identify the DNA sequence based on the change in electrical properties of the at least one transistor.
2. The system of claim 1 , wherein the at least one transistor comprises a source lead, a gate lead, and a drain lead, and the source lead, the gate lead, and the drain lead each electrically couple to an external connector, the external connector supplies a voltage across the drain-source lead and a bias across the gate-source lead, and couples to an electrical properties measuring device.
3. The system of claim 1 , wherein the electrical properties measuring device is an amp-meter, a voltmeter, or a computer.
4. The system of claim 1 , wherein the bottom portion of the sample well forms an aperture and the aperture contacts and forms a liquid-tight seal with the biological sample sensor, such that when the biological sample is introduced to the sample well, the biological sample contacts a top surface of the biological sample sensor.
5. The system of claim 1 , wherein the biological sample is a suspension of a DNA sample.