IP Library › Granted Patent US 10,799,467
Granted Patent B2
US 10,799,467 · App. 14/685,753 · Granted Oct 13, 2020

Use of the phytocannabinoid cannabidivarin (CBDV) in the treatment of epilepsy

Inventors: Ben Whalley (Reading, GB); Claire Williams (Reading, GB); Gary Stephens (Reading, GB); Takashi Futamura (Osaka, JP)
Assignees: GW Pharma Limited; Otsuka Pharmaceutical Co. Limited
A61K31/05A61K31/19A61K31/352A61K31/40A61K31/515A61K36/185A61K45/06
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,799,467
App. No.
14/685,753
Granted
Oct 13, 2020
Kind
B2
Abstract

This invention relates to the use of the phytocannabinoid cannabidivarin (CBDV) and combinations of the phytocannabinoid CBDV with tetrahydrocannabivarin (THCV) and cannabidiol (CBD) in the treatment of epilepsy. The invention further relates to the use of the phytocannabinoid CBDV in combination with standard anti-epileptic drugs (SAEDs). Preferably the SAED is one of ethosuximide, valproate or phenobarbital.

Claims (6)

1. A method for the treatment of partial seizures, which comprises administering to a subject in need thereof a therapeutically effective amount of the phytocannabinoid CBDV, wherein the CBDV is present as the only active cannabinoid.

2. The method of claim 1 , wherein the partial seizure to be treated is a temporal lobe seizure.

3. The method of claim 1 , wherein the CBDV is used in combination with a standard anti-epileptic drug.

4. The method of claim 3 , wherein the standard anti-epileptic drug is phenobarbital.

5. The method of claim 3 , wherein the standard anti-epileptic drug is ethosuximide.

6. The method of claim 3 , wherein the standard antiepileptic drug is valproate.

Assignments (4)
CHANGE OF NAME Recorded May 13, 2025
From: GW PHARMA LIMITED
To: JAZZ PHARMACEUTICALS OPERATIONS UK LIMITED
Reel/Frame 071103/0738 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 12, 2023
From: OTSUKA PHARMACEUTICAL CO., LTD.
To: GW PHARMA LTD.
Reel/Frame 063631/0588 →
SECURITY AGREEMENT Recorded Jul 22, 2021
From: GW PHARMA LIMITED; GW RESEARCH LIMITED
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 056958/0493 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2015
From: WHALLEY, BEN; WILLIAMS, CLAIRE; STEPHENS, GARY; FUTAMURA, TAKASHI
To: GW PHARMA LIMITED; OTSUKA PHARMACEUTICAL CO. LIMITED
Reel/Frame 036305/0490 →