IP Library Granted Patent US 9,504,685
Granted Patent B2
US 9,504,685 · App. 14/695,775 · Granted Nov 29, 2016

Method for treating a pulmonary hypertension condition

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Quick Facts
Patent No.
US 9,504,685
App. No.
14/695,775
Granted
Nov 29, 2016
Kind
B2
Abstract

A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a therapeutically effective amount of ambrisentan, wherein, at baseline, time from first diagnosis of the condition in the subject is not greater than about 2 years.

Claims (6)

1. A method for treating a human patient exhibiting a pulmonary arterial hypertension (PAH) of WHO Functional Class IV at baseline, comprising administering to the patient a therapeutically effective amount of ambrisentan.

2. The method of claim 1 , wherein the PAH is further associated with a connective tissue disease (CTD).

3. The method of claim 1 , wherein the ambrisentan is administered in a daily dosage amount of about 1 mg to about 25 mg.

4. The method of claim 3 , wherein the ambrisentan is administered in a daily dosage amount of about 2.5 mg to about 10 mg.

5. The method of claim 4 , wherein the administration continues for 12 weeks.

6. The method of claim 1 , wherein the administration is initiated within 2 years following diagnosis of the PAH condition.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2015
From: GILEAD COLORADO, INC.
To: GILEAD SCIENCES, INC.
Reel/Frame 036832/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2015
From: GERBER, MICHAEL J.; DUFTON, CHRISTOPHER
To: GILEAD COLORADO, INC.
Reel/Frame 036833/0065 →