Occlusion Device
Provided herein is an occlusion device for intrasaccular implantation and/or vascular occlusion comprising: (a) a substantially solid marker having a proximal end, and a distal end; and (b) a low profile resilient mesh body attached to the distal end of the marker, the body having a delivery shape and a deployed shape capable of conforming to aneurysm walls; wherein the body has a diameter greater than a diameter of an aneurysm to be treated. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device disclosed herein are also disclosed.
1. A kit for treatment and/or amelioration of an aneurysm; the kit comprising
a. an occlusion device for intrasaccular implantation consisting of (i) a substantially solid marker having a proximal end, and a distal end; and (ii) a resilient mesh body attached to the distal end of the marker, the body having a delivery shape and a deployed shape capable of conforming to aneurysm walls; wherein the body is a dual layer of the resilient mesh folded over onto itself to create a circumferential fold line around the circumference of the body, and folded over ends of the resilient mesh, and wherein all of the folded over ends of the dual layer of mesh are within the marker; and
b. a delivery system or detachment system corresponding to the occlusion device.
2. The kit of claim 1 , wherein the delivery system is a micro catheter, catheter, guide wire, or pusher wire.
3. The kit of claim 1 , wherein the detachment system is an electrolytic detachment system.
4. An implantable device for vessel occlusion consisting of: (a) a substantially solid marker having a proximal end, and a distal end; and (b) a resilient mesh body attached to the distal end of the marker, the body having a delivery shape and a deployed shape capable of conforming to vessel walls; wherein the body is a dual layer of the resilient mesh folded over onto itself to create a circumferential fold line around the circumference of the body, and folded over ends of the resilient mesh, and wherein all of the folded over ends of the dual layer of mesh are within the marker.
5. The occlusion device of claim 4 , wherein the deployed shape of the body is capable of apposing an aneurysm dome.
6. The occlusion device of claim 4 , wherein the proximal end of the marker is capable of sealing an aneurysm neck.
7. The occlusion device of claim 4 , wherein the marker is a radiopaque marker.
8. The occlusion device of claim 4 , wherein the marker is a detachment junction to deploy the occlusion device.
9. The occlusion device of claim 4 , wherein the marker is an attachment junction to retrieve the occlusion device.
10. The occlusion device of claim 4 , wherein the marker comprises a rigid member.
11. The occlusion device of claim 4 , wherein the marker is a solid ring.
12. The implantable device of claim 4 , wherein the body is configured to have a diameter greater than a diameter of an aneurysm or vessel to be treated; and wherein the body has a height that is between about 10-20% of its width.
13. The occlusion device of claim 12 , wherein the body has a height that is between about 12-18% of its width.
14. The occlusion device of claim 12 , wherein the body has a height that is between about 14-16% of its width.
15. The occlusion device of claim 12 , wherein the body has a height that is about 15% of its width.