IP Library › Patent Application 14705150
Patent Application
App. No. 14/705,150

RECOMBINASE POLYMERASE AMPLIFICATION REAGENTS AND KITS

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Quick Facts
Patent No.
US None
App. No.
14/705,150
Abstract

This disclosure describes kits, reagents and methods for Recombinase Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and related proteins, to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The disclosed kits, reagents and methods have the advantage of not requiring thermocycling or thermophilic enzymes, thus offering easy and affordable implementation and portability relative to other amplification methods.

Claims (3)

1 - 39 . (canceled)

40 . A frieze dried pellet for a recombinase polymerase amplification process of DNA amplification of a target nucleic acid molecule, comprising: trehalose, and wherein said pellet does not contain polyethylene glycol.

41 . The frieze dried pellet of claim 40 , wherein said pellet comprises 2.5%-7.5% weight/lyophilization mixture volume of trehalose.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2020
From: ALERE SAN DIEGO INC.
To: ABBOTT DIAGNOSTICS SCARBOROUGH, INC.
Reel/Frame 054604/0936 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 6, 2015
From: PIEPENBURG, OLAF; ARMES, NIALL A.
To: ALERE SAN DIEGO INC.
Reel/Frame 035575/0571 →