IP Library Granted Patent US 9,475,024
Granted Patent B2
US 9,475,024 · App. 14/707,237 · Granted Oct 25, 2016

Single column immunological test elements

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Quick Facts
Patent No.
US 9,475,024
App. No.
14/707,237
Granted
Oct 25, 2016
Kind
B2
Abstract

A plurality of individual single column test elements are provided for use in a clinical testing apparatus in an open-topped cartridge in which each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. The number of individual test elements provided in a cartridge can be varied, depending on the test(s) to be performed.

Claims (13)

1. A cartridge for conducting immunological testing, the cartridge comprising:

a frame defining an enclosure that is sized to receive and maintain a predetermined number of individual test elements in close fitting and adjacent relation with each other in an array; and

a plurality of the individual test elements releasably retained within the enclosure in a linear array, each of the individual test elements comprising a single test column containing a test material and having a cover strip.

2. The cartridge as recited in claim 1 , wherein each individual test element is made from an optically transparent material.

3. The cartridge as recited in claim 2 , in which the enclosure is made from an optically transparent material.

4. The cartridge as recited in claim 1 , wherein the contained test material includes a quantity of an inert material.

5. The cartridge as recited in claim 4 , wherein the inert material is one of glass beads or gel material.

6. The cartridge as recited in claim 1 , wherein the enclosure is sized and configured to retain between 2 and 8 individual test elements, the number of individual test elements being dependent on the test(s) to be performed.

7. The cartridge as recited in claim 1 , in which the cover strip of each test element is pierceable to enable a patient sample to be dispensed into the test column.

8. The cartridge as recited in claim 7 , in which each individual test element is configured to produce a perceivable reaction between the patient sample and test material.

9. The cartridge as recited in claim 8 , wherein the contained test material further includes a reagent containing at least one of an antibody and an antigen.

10. The cartridge as recited in claim 9 , wherein the reaction is an agglutination reaction.

11. The cartridge as recited in claim 1 , in which a plurality of the cartridges are used in a clinical immunodiagnostic apparatus.

Assignments (5)
SECURITY AGREEMENT Recorded Aug 22, 2025
From: CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; QUIDEL CARDIOVASCULAR INC.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 072526/0643 →
RELEASE (REEL 060220 / FRAME 0711) Recorded Aug 22, 2025
From: BANK OF AMERICA, N.A.
To: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
Reel/Frame 072577/0536 →
RELEASE OF SECURITY INTEREST Recorded May 31, 2022
From: BANK OF AMERICA, N.A.
To: ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC
Reel/Frame 060219/0571 →
SECURITY AGREEMENT Recorded May 31, 2022
From: QUIDEL CORPORATION; BIOHELIX CORPORATION; DIAGNOSTIC HYBRIDS, INC.; QUIDEL CARDIOVASCULAR INC.; ORTHO-CLINICAL DIAGNOSTICS, INC.; CRIMSON U.S. ASSETS LLC; CRIMSON INTERNATIONAL ASSETS LLC; MICRO TYPING SYSTEMS, INC.
To: BANK OF AMERICA, N.A.
Reel/Frame 060220/0711 →
SECURITY AGREEMENT Recorded Nov 6, 2018
From: ORTHO-CLINICAL DIAGNOSTICS, INC.
To: BARCLAYS BANK PLC
Reel/Frame 047435/0065 →