IP Library › Patent Application 14729605
Patent Application
App. No. 14/729,605

Method of Treating Skin Disorders

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Quick Facts
Patent No.
US None
App. No.
14/729,605
Abstract

A skin care product includes a compound of Formula I, IA, or IB (e.g., anatabine), or a salt thereof, and a suitable cosmetic or pharmaceutical vehicle. In some aspects, the skin care product is a paste, cream, lotion, gel, moisturizer, cleanser, or sunscreen. In some embodiments, the skin care product is applied topically to reduce inflammation, redness, and/or irritation, and/or to improve the appearance of the skin. In other embodiments, the skin care product is applied topically to treat an autoimmune and/or dermatological condition such as acne, psoriasis, and/or rosacea.

Claims (20)

1 . A method of treating a skin disorder comprising administering a composition containing a therapeutically effective amount of an isolated form of a compound of Formula I:

wherein:

R represents hydrogen or C 1 -C 5 alkyl;

R′ represents hydrogen or C 1 -C 7 alkyl;

X represents halogen or C 1 -C 7 alkyl;

“a” represents an integer from 0-4;

“b” represents an integer from 0-8; and

the dotted line within the piperidine ring represents (i) a carbon/carbon or carbon/nitrogen double bond and a carbon/carbon double bond conjugated thereto, or (ii) a carbon/nitrogen double bond;

or a pharmaceutically acceptable salt thereof; and

a pharmaceutically acceptable vehicle therefor.

2 . The method of claim 1 , wherein the compound of Formula I is anatabine or a salt thereof.

3 . The method of claim 1 , wherein the compound of Formula I is anatabine citrate.

4 . The method of claim 1 , wherein the composition is administered topically.

5 . The method of claim 1 , wherein the skin disorder is selected from the group consisting of psoriasis, rosacea, and acne.

6 . The method of claim 5 , wherein the skin disorder is psoriasis.

7 . The method of claim 5 , wherein the skin disorder is rosacea.

8 . The method of claim 5 , wherein the skin disorder is acne.

9 . A method of treating psoriasis comprising administering a composition containing a therapeutically effective amount of anatabine or a pharmaceutically acceptable salt thereof.

10 . The method of claim 9 , wherein the pharmaceutically acceptable salt is anatabine citrate.

11 . The method of claim 10 , wherein the composition is administered topically.