Lyophilization
Embodiments of methods, systems, and apparatuses for lyophilizing, storing, and transfusing materials are described. In embodiments, the materials may include whole blood or a component of whole blood such as plasma.
1. A container for lyophilizing, storing, and transfusing a blood component, the container comprising:
a first wall made from a porous material comprising a polymer, the first wall having a first permeability to water vapor;
a second wall attached to the first wall to define an interior volume of the container, wherein the second wall comprises a polymeric material and has a second permeability to water vapor that is lower than the first permeability to water vapor;
the interior volume of the container holding a blood component for lyophilization; and
a third wall positioned adjacent the first wall to provide protection for the first wall, wherein the third wall has a third permeability to water vapor that is greater than or equal to the first permeability to water vapor.
2. The container of claim 1 , wherein the first wall is water resistant.
3. The container of claim 2 , wherein the first permeability to water vapor comprises at least 15 perms.
4. The container of claim 3 , wherein the first wall has a water resistance of greater than 100 cm.
5. The container of claim 1 , further comprising a port connector between the first wall and the second wall.
6. The container of claim 1 , wherein the blood component comprises human plasma and after a lyophilization process, the interior volume of the container comprises lyophilized human plasma.