MULTILAYER FILM COMPRISING A CONTACT LAYER, CORE LAYER AND OUTER LAYER FOR THE WALL OF A SINGLE-USE POUCH
A multilayer film includes a contact layer, a core layer, and an outer layer, the contact and core layers being integral with a first tie layer; and the outer and core layers being integral with a second tie layer; the contact layer includes a copolymer of ethylene and α-olefin having a density from 0.870 to 0.910 g/cm 3 , alone or in mixture with a polyolefin having a density from 0.910 to 0.940 g/cm 3 ; the core layer includes a flex-crack resistant ethylene vinyl alcohol copolymer having an ethylene content from 25 to 48 mol % or a mixture of an ethylene vinyl alcohol copolymer having an ethylene content from 25 to 48 mol %, and an ionomer acid ethylene copolymer; the outer layer includes a polyolefin having a density from 0.910 to 0.940 g/cm 3 , alone or in mixture with a copolymer of ethylene and α-olefin having a density from 0.870 to 0.910 g/cm 3 .
1 - 18 . (canceled)
19 . A multilayer film for manufacturing a pouch, said multilayer film comprising:
a contact layer,
a core layer,
an outer layer,
wherein:
the contact layer and the core layer are made integral with a first tie layer,
the outer layer and the core layer are made integral with a second tie layer,
the contact layer comprises (A) a copolymer of ethylene and α-olefin having a density in the range of 0.870 g/cm 3 to 0.910 g/cm 3 , alone or in mixture with (B) a polyolefin having a density in the range of 0.910 g/cm 3 to 0.940 g/cm 3 ,
the core layer comprises (C′) a flex-crack resistant ethylene vinyl alcohol copolymer having a content of ethylene in the range of 25 to 48 mol % or a mixture of (C) an ethylene vinyl alcohol copolymer having a content of ethylene in the range of 25 to 48 mol % and (D) an ionomer acid ethylene copolymer,
the outer layer comprises (E) a polyolefin having a density in the range of 0.910 g/cm 3 to 0.940 g/cm 3 , alone or in mixture with (F) a copolymer of ethylene and α-olefin having a density in the range of 0.870 g/cm 3 to 0.910 g/cm 3 ,
the first tie layer and second tie layer comprise independently of each other (G) a copolymer of polyolefin grafted with a carboxylic acid or an anhydride of carboxylic acid, alone or in mixture with (H) a copolymer of polyolefin.
20 . The multilayer film according to claim 19 , wherein the copolymer of ethylene and α-olefin (A) is a plastomer polyolefin having from 4 to 8 carbon atoms, in particular a linear low density copolymer of ethylene and oct-1-ene made from a process utilizing a metallocene catalyst.
21 . The multilayer film according to claim 19 , wherein polyolefin (B) is a homopolymer of ethylene, in particular a low density polymer of ethylene.
22 . The multilayer film according to claim 19 , wherein the ethylene vinyl alcohol copolymer (C) is flex-crack resistant.
23 . The multilayer film according to claim 19 , wherein the copolymer (D) is an acrylic acid copolymer of ethylene ionomer wherein the carboxylate groups are associated with zinc cations.
24 . The multilayer film according to claim 19 , wherein the polyolefin (E) is a copolymer of ethylene with one or more olefin having from 4 to 8 carbon atoms, in particular a linear low density copolymer of ethylene and hexene.
25 . The multilayer film according to claim 19 , wherein the copolymer (F) is a plastomer polyolefin having from 4 to 8 carbon atoms, in particular a linear low density copolymer of ethylene and oct-1-ene made from a process utilizing a metallocene catalyst.
26 . The multilayer film according to claim 19 , wherein the copolymer (G) is a copolymer of ethylene grafted with maleic anhydride.
27 . The multilayer film according to claim 19 , wherein the copolymer (H) is a plastomer polyolefin having from 4 to 8 carbon atoms, in particular a linear low density copolymer of ethylene and oct-1-ene made from a process utilizing a metallocene catalyst.
28 . The multilayer film according to claim 19 , wherein the contact layer comprises a mixture of (A) and (B) with a mass ratio (B)/(A) less than or equal to 95/5, preferably in the range of 5/95 to 95/5, more preferably in the range of 0.2 to 5, even more preferably in the range of 0.2 to 2.
29 . The multilayer film according to claim 19 , wherein the core layer comprises a mixture of (C) an ethylene vinyl alcohol copolymer having a content of ethylene in the range of 25 to 48 mol % and (D) an ionomer acid ethylene copolymer with a mass ratio (C)/(D) in the range of 95/5 to 55/45, preferably in the range of 10 to 19, more preferably in the range of 15 to 19.
30 . The multilayer film according to claim 19 , wherein the outer layer comprises a mixture of (E) and (F) with a mass ratio (E)/(F) more than or equal to 5/95, preferably in the range of 5/95 to 100/0, more preferably in the range of 1 to 5, even more preferably in the range of 1 to 2.5.
31 . The multilayer film according to claim 19 , wherein the first tie layer and second tie layer comprise independently of each other a mixture of (G) and (H) with a mass ratio (H)/(G) less than or equal to 95/5, preferably in the range of 5/95 to 95/5, more preferably in the range of 0.2 to 5, even more preferably in the range of 0.2 to 2.5.
32 . The multilayer film according to claim 19 , wherein the contact layer contains no additives or limited amounts, preferably less than 0.10 wt %, more preferably less than 0.07 wt %, of additives able to release a degradation compound further to gamma irradiation that can slow down or delay cellular growth, such as Tris(2,4-ditert-butylphenyl)phosphite.
33 . The multilayer film according to claim 19 , said multilayer film further comprising one or several intermediate layers between two of any layers of the film.
34 . A process for manufacturing the multilayer film according to claim 19 , comprising coextrusion of the contact layer, first tie layer, core layer, second tie layer and outer layer.
35 . A single-use pouch whose wall comprises the multilayer film according to claim 19 .
36 . A bioreactor comprising the single-use pouch according to claim 35 .