IP Library Granted Patent US 9,801,578
Granted Patent B2
US 9,801,578 · App. 14/762,447 · Granted Oct 31, 2017

Reduced size optical coupler for fluorescence detection

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Quick Facts
Patent No.
US 9,801,578
App. No.
14/762,447
Granted
Oct 31, 2017
Kind
B2
Abstract

Optical systems are disclosed for use in identifying an analyte, such as glucose in blood or interstitial fluid (ISF), using a biomaterial, such as glucose binding protein (GBP), that is brought into contact with the analyte. An optical system includes a first filter adapted to reflect light emitted from a light-emitting diode to illuminate a fluorescent body, and further adapted to transmit light emitted from the fluorescent body, and a second filter adapted to separate light transmitted by the first filter into signal band light and reference band light.

Claims (41)

1. An optical system comprising:

a first filter adapted to reflect light emitted from a light-emitting diode in a first frequency band to illuminate a fluorescent body, and further adapted to transmit light emitted from the fluorescent body in a second frequency band;

a second filter adapted to separate light transmitted by the first filter by reflecting a signal band light and transmitting a reference band light; and

a single optical connector comprising at least two integral lenses and an inclined surface upon which said first filter is mounted and said second filter is positioned to direct the reflected signal band light through the inclined surface.

2. The optical system of claim 1 , further comprising a photodiode adapted to receive at least one selected from the set consisting of signal band light and reference band light transmitted by the second filter.

3. The optical system of claim 1 , wherein the first filter comprises a first glass filter comprising a first dichroic filter coating on a first surface of the first glass filter,

wherein the first dichroic filter is adapted to reflect light emitted by the light-emitting diode and is further adapted to transmit light emitted from the fluorescent body.

4. The optical system of claim 1 , wherein the first filter is further adapted to block wavelengths outside of a signal band wavelength range and a reference band wavelength range.

5. The optical system of claim 1 , wherein the first filter comprises a glass filter coated by a dichroic filter coating.

6. The optical system of claim 1 , wherein the second filter comprises a second glass filter comprising a second dichroic filter coating on a first surface of the second glass filter,

wherein the second dichroic filter is adapted to reflect light of wavelengths associated with a signal band, and is further adapted to transmit light of wavelengths associated with a reference band.

7. The optical system of claim 1 , wherein wavelengths associated with the signal band are shorter than wavelengths associated with the reference band.

8. The optical system of claim 1 , wherein the second filter comprises a diffraction grating layer adapted to spread light in accordance with wavelength of light.

9. The optical system of claim 1 , wherein the first filter and the second filter are formed on opposing sides of a filter element.

10. An optical system comprising:

a first filter adapted to reflect light emitted from a light-emitting diode in a first frequency band to illuminate a fluorescent body, and further adapted to transmit light emitted from the fluorescent body in a second frequency band;

a second filter adapted to separate light transmitted by the first filter by reflecting a first beam of light in a signal band and transmitting a second beam of light in a reference band; and

a single optical connector comprising at least two integral lenses and an inclined surface upon which said first filter is mounted and said second filter is positioned to direct the first beam of light through the inclined surface, wherein the second filter is adapted to separate light transmitted by the first filter substantially evenly into the first beam and the second beam.

11. The optical system of claim 10 , further comprising a photodiode adapted to receive at least one selected from the set consisting of the first beam and the second beam.

12. The optical system of claim 11 , wherein the photodiode comprises a filter that blocks wavelengths outside of one selected from the set consisting of a signal band wavelength range and a reference band wavelength range.

13. The optical system of claim 12 , wherein the filter comprises a filter coating.

14. The optical system of claim 10 , wherein the first filter and the second filter are formed into a unitary component.

15. An optical coupler comprising:

a fiber adapted to contact a fluorescent body;

a light-emitting diode;

a first filter adapted to reflect light emitted from the light-emitting diode in a first frequency band to illuminate the fluorescent body through the fiber, and further adapted to transmit light emitted from the fluorescent body in a second frequency band;

a second filter adapted to separate light transmitted by the first filter by reflecting a signal band light and transmitting a reference band light;

a single optical connector comprising at least two integral lenses and an inclined surface upon which said first filter is mounted and said second filter is positioned to direct the reflected signal band light through the inclined surface; and

a photodiode adapted to receive at least one selected from the set consisting of signal band light and reference band light transmitted by the second filter.

16. The optical coupler of claim 15 , further comprising:

an light-emitting diode lens adapted to focus emitted from the light-emitting diode toward the first filter;

a fiber lens adapted to focus light toward the fiber, and further adapted to focus light from the fiber; and

a detector lens adapted to focus light onto the photodiode.

17. The optical coupler of claim 16 , wherein the light-emitting diode lens and the fiber lens are integrally formed.

18. An optical sensor comprising:

the optical coupler of claim 15 ; and

a base with a bottom surface and a top surface, wherein the bottom surface is adherable to skin,

wherein the light-emitting diode is disposed on the top surface of the base, and

wherein the photodiode is disposed on the top surface of the base.

19. The optical system of claim 15 , wherein the fluorescent body comprises a biomaterial.

20. The optical system of claim 15 , wherein the fluorescent body comprises a glucose binding protein.

Assignments (9)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 24, 2025
From: EMBECTA CORPORATION
To: INSULET CORPORATION
Reel/Frame 073781/0220 →
RELEASE OF SECURITY INTEREST Recorded Nov 10, 2025
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: EMBECTA CORP.
Reel/Frame 073531/0700 →
RELEASE OF SECURITY INTEREST Recorded Nov 10, 2025
From: MORGAN STANLEY SENIOR FUNDING, INC.
To: EMBECTA CORP.
Reel/Frame 073531/0774 →
RELEASE OF SECURITY INTEREST Recorded Nov 10, 2025
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: EMBECTA CORP.
Reel/Frame 073531/0683 →
FIRST LIEN PATENT SECURITY AGREEMENT (SENIOR SECURED NOTES) Recorded Mar 14, 2023
From: EMBECTA CORP.
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 063083/0071 →
FIRST LIEN PATENT SECURITY AGREEMENT (SENIOR SECURED NOTES) Recorded Mar 13, 2023
From: EMBECTA CORP.
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 063780/0053 →
FIRST LIEN TERM PATENT SECURITY AGREEMENT Recorded Mar 10, 2023
From: EMBECTA CORP.
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 063028/0318 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2022
From: BECTON, DICKINSON AND COMPANY
To: EMBECTA CORP.
Reel/Frame 059721/0617 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2017
From: WEBER, AARON; TRACY, DAVID; SALEMME, JAMES; PRUDDEN, JOHN
To: BECTON, DICKINSON AND COMPANY
Reel/Frame 043706/0649 →