Cell culturing and/or biomanufacturing system
View Patent ↗The present invention relates to systems and methods for optimising the usage of laboratory and cell culturing space for cell culture and biomanufacturing. The invention provides a system and method that can be used to provide a plurality of workstations and/or storage bays for bioreactors in cell culturing and/or biomanufacturing facilities.
1. A system for cell culture and/or biomanufacturing, the system comprising:
a base unit comprising:
a frame supporting walls and a movable platform to define a chamber therein;
a stacking unit comprising:
a frame supporting side walls, a back wall, a ceiling, and a movable platform to define an upper chamber and a lower chamber therein, wherein said lower chamber is dimensioned to receive said base unit therein; and
a guard unit comprising:
a frame supporting side walls, a movable platform, and an openable front wall to define an upper chamber and a lower chamber therein, wherein said lower chamber is dimensioned to partially receive said stacking unit therein; and
legs supporting said frame and dimensioned to receive said base unit therebetween,
wherein said base unit, said stacking unit, and said guard unit are interconnected to provide a plurality of workstations and/or storage bays for a bioreactor.
2. The system according to claim 1 , wherein said base unit and/or said stacking unit and/or said guard unit are movable.
3. The system according to claim 2 , wherein said base unit and/or said stacking unit and/or said guard unit comprise wheels.
4. The system according to claim 3 , wherein said wheels are reversibly lockable.
5. The system according to claim 1 , further comprising a connection to utilities selected from the group consisting of electricity, water, nitrogen, oxygen, air and carbon dioxide.
6. The system according to claim 1 , further comprising a connection to a waste disposal outlet.
7. The system according to claim 1 , further comprising a connection to a refrigeration unit.
8. The system according to claim 1 , wherein said platform within said base unit is movable in a vertical plane.
9. The system according to claim 1 , wherein said lower platform in said stacking unit is movable in a horizontal and/or a vertical plane.
10. The system according to claim 1 , wherein said platform in said guard unit is movable in a horizontal and/or a vertical plane.
11. The system according to claim 1 , wherein said openable front wall of said guard unit is a sliding wall.
12. The system according to claim 1 , wherein said chamber of said base unit, said stacking unit, and said guard unit comprise internal sterilizable surfaces.
13. The system according to claim 1 , wherein said base unit, said stacking unit, and said guard unit have a cuboid configuration.
14. The system according to claim 1 , wherein at least one of said platform in said base unit and said platform in said stacking unit can support at least one bioreactor.
15. The system according to claim 14 , wherein said bioreactor is a movement based bioreactor such as a WAVE bioreactor.
16. The system according to claim 14 , wherein said bioreactor is a stir tank bioreactor.
17. The system according to claim 1 , wherein at least one of said platforms is movable by an electronic device or a pneumatic device.
18. A method for cell culture, the method comprising:
growing a cell culture in at least one bioreactor in a system according to claim 1 to produce a plurality of cells.