IP Library Granted Patent US 10,098,912
Granted Patent B2
US 10,098,912 · App. 14/772,139 · Granted Oct 16, 2018

Treatment and prophylaxis of radiation dermatitis

Inventors: Mark Lait (Hertford Hertfordshire, GB); George Bishop (Carlstadt, NJ)
Assignee: WATER-JEL EUROPE LLP
A61K35/20A61K9/0009A61K9/0014A61K9/06A61K31/047A61K31/12A61K31/133A61K31/216A61K31/275A61K38/018A61K47/10A61K47/14A61K47/18A61K47/32A61K47/36A61K47/46
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Quick Facts
Patent No.
US 10,098,912
App. No.
14/772,139
Granted
Oct 16, 2018
Kind
B2
Abstract

The present disclosure relates to topical formulations comprising purified water, milk protein fluid and thickener, in particular a hydrogel and a lotion, and their use in treatment of radiation dermatitis, in particular in a two-step process for the treatment of radiation dermatitis.

Claims (17)

1. A topical formulation for the treatment of radiation dermatitis consisting essentially of:

10% octocrylene,

3% octinoxate,

3% avobenzone,

58.8% purified water,

8% C 12-15 alkyl benzoate,

5% milk protein,

4% caprylyl methicone,

1% ceteareth-20 and ceteryl alcohol,

0.7% ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymer,

1% glyceryl stearate self-emulsifying,

1.2% glyceryl stearate,

1% glyceryl stearate citrate,

1% phenoxyethanol and ethylhexylglycerine,

0.2% edetate disodium,

2% corn starch,

wherein all the % values are expressed in terms of weight percent, and wherein viscosity is in the range 25,000 to 130,000 cP.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 8, 2021
From: SAFEGUARD MEDICAL HOLDCO, LLC
To: RADIADERM LIMITED
Reel/Frame 057742/0536 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2020
From: WATER-JEL EUROPE, LLP
To: SAFEGUARD MEDICAL HOLDCO, LLC
Reel/Frame 053682/0460 →
RELEASE OF SECURITY INTEREST Recorded May 4, 2020
From: WEBSTER BANK, NATIONAL ASSOCIATION
To: WATER-JEL EUROPE, LLP
Reel/Frame 052564/0770 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2016
From: LAIT, MARK; BISHOP, GEORGE
To: WATER-JEL EUROPE LLP
Reel/Frame 040176/0822 →
SECURITY INTEREST Recorded Jun 9, 2016
From: WATER-JEL EUROPE, LLP
To: BROOKSIDE MEZZANINE FUND III, L.P.
Reel/Frame 038856/0593 →
RELEASE OF SECURITY INTEREST Recorded Jun 3, 2016
From: BROOKSIDE MEZZANINE FUND III, L.P.
To: WATER-JEL EUROPE, LLP
Reel/Frame 038801/0499 →
SECURITY AGREEMENT Recorded Jun 2, 2016
From: WATER-JEL EUROPE, LLP
To: WEBSTER BANK, NATIONAL ASSOCIATION
Reel/Frame 038864/0675 →
Priority Claims (1)
GB 1304041.5 · Mar 6, 2013 · national
Continuity (2)
Provisional Application 61773225 · Mar 6, 2013
Related Publication 20160015752A1 · Jan 21, 2016