Influenza virus reassortment
New influenza donor strains for the production of reassortant influenza B viruses are provided.
1. A reassortant influenza virus comprising:
the PA segment of SEQ ID NO: 11, the PB1 segment of SEQ ID NO: 12, the PB2 segment of SEQ ID NO: 13, the NP segment of SEQ ID NO: 14, the NS segment of SEQ ID NO: 35 and the M segment of SEQ ID NO: 34.
2. The reassortant influenza virus of claim 1 , wherein the virus is grown in cell culture.
3. The reassortant influenza virus of claim 1 , wherein the virus is grown in eggs.
4. An expression system comprising one or more expression construct(s) which encode the reassortant influenza virus of claim 1 .
5. A vaccine made from the reassortant influenza virus of claim 1 .
6. The reassortant influenza virus of claim 1 further comprising HA and NA segments.
7. A reassortant influenza virus comprising:
a PA segment comprising the amino acid sequence encoded by SEQ ID NO: 11, a PB1 segment comprising the amino acid sequence encoded by SEQ ID NO: 12, a PB2 segment comprising the amino acid sequence encoded by SEQ ID NO: 13, an NP segment comprising the amino acid sequence encoded by SEQ ID NO: 14, an NS segment comprising the amino acid sequence encoded by SEQ ID NO: 35 and an M segment comprising the amino acid sequence encoded by SEQ ID NO: 34.
8. The reassortant influenza virus of claim 7 , wherein the virus is grown in cell culture.
9. The reassortant influenza virus of claim 7 , wherein the virus is grown in eggs.
10. An expression system comprising one or more expression construct(s) which encode the reassortant influenza virus of claim 7 .
11. A vaccine made from the reassortant influenza virus of claim 7 .
12. The reassortant influenza virus of claim 7 further comprising HA and NA segments.