Arginine methyltransferase inhibitors and uses thereof
View Patent ↗Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
1. A compound of formula:
or a pharmaceutically acceptable salt thereof.
2. The compound of claim 1 , wherein the compound is:
3. The compound of claim 1 , wherein the compound is a pharmaceutically acceptable salt of:
4. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
5. A pharmaceutical composition comprising a compound of claim 2 , and a pharmaceutically acceptable excipient.
6. A pharmaceutical composition comprising a compound of claim 3 , and a pharmaceutically acceptable excipient.
7. A kit or packaged pharmaceutical comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and instructions for use thereof.
8. A kit or packaged pharmaceutical comprising a compound of claim 2 , and instructions for use thereof.
9. A kit or packaged pharmaceutical comprising a compound of claim 3 , and instructions for use thereof.