IP Library Granted Patent US 11,246,878
Granted Patent B2
US 11,246,878 · App. 14/775,952 · Granted Feb 15, 2022

Compositions and products for infectious or inflammatory diseases or conditions

Inventor: Huiru Wang (Willowbrook, IL)
Assignee: B&H BIOTECHNOLOGIES, LLC
A61K31/7008A23K20/142A23K20/147A23L33/10A23L33/17A23L33/175A61K9/0019A61K9/0043A61K9/0095A61K31/198A61K45/06C07C321/14C07H15/12A23V2002/00A61K9/08A61K9/10A61K9/107A61K47/02
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Quick Facts
Patent No.
US 11,246,878
App. No.
14/775,952
Granted
Feb 15, 2022
Kind
B2
Abstract

Composition and methods for treating infectious and inflammatory diseases using saccharide based products and therapies. Products can be implemented as a nutritional supplement, a food, a feed, a food additive, a feed additive, a therapeutic product, a rehydration salt, or a rehydration solution. The present disclosure relates generally to the fields of compositions and products containing the compositions, and the use of the compositions or the products for preventing and/or treating infectious or inflammatory diseases or conditions in particular gastrointestinal and respiratory diseases (diarrhea and influenza infections) or inflammatory.

Claims (20)

1. A composition, comprising:

about 0.01 mg/mL to about 20 mg/mL of N-acetylneuraminic acid;

about 0.01 mg/mL to about 20 mg/mL of N-acetylneuraminic acid methyl ester; and

about ¼ to about ¾ of the manufacturer's recommended dose of Tamiflu for the treatment of influenza; or

about ¼ to about ¾ of the manufacturer's recommended dose of Enrofloxacin for the treatment of rotavirus infection or diarrhea; or

about ¼ to about ¾ of the manufacturer's recommended dose of Tilmicosin for the treatment of respiratory infections, respiratory syndrome, asthma, or other respiratory disorders; or

about ¼ to about ¾ of the manufacturer's recommended dose of Cephradine for the treatment of diarrhea, dehydration, or gastroenteritis; or

about ¼ to about ¾ of the manufacturer's recommended dose of Tulathromycin for the treatment of respiratory infections or disorders.

2. The composition of claim 1 , wherein the composition is a nutritional supplement, a food, a feed, a medicated food additive, a medicated feed additive, a therapeutic composition, a rehydration salt, or a rehydration solution.

3. The composition of claim 1 , wherein the composition is used to treat infectious and inflammatory diseases caused by viral or bacterial infections, gastroenteritis, nutritional problems, food intolerances, inflammation, allergy, gastrointestinal and respiratory diseases or conditions, cancers or autoimmune diseases.

4. The composition of claim 1 , wherein the composition is in the form of a tablet, capsule, pill, powder, granule, elixir, tincture, solution, suspension, syrup, emulsion, nasal drop or spray, an injectable, an infusion, or a form conjugated to a nano-particle.

5. The composition of claim 1 , wherein the composition comprises about 2 mg/mL to about 20 mg/mL N-acetylneuraminic acid.

6. The composition of claim 1 , wherein the composition further comprises N-acetylglucosamine.

7. The composition of claim 1 , wherein the composition comprises about 2 mg/mL to about 20 mg/mL of N-acetylneuraminic acid methyl ester.

8. The composition of claim 1 , wherein the composition comprises about 2 mg/g to about 20 mg/g of the N-acetylneuraminic acid.

9. The composition of claim 8 , wherein the composition comprises about 2 mg/g to about 20 mg/g of N-acetylneuraminic acid methyl ester.

10. The composition of claim 1 , wherein the composition comprises about 2 mg/g to about 20 mg/g of N-acetylneuraminic acid methyl ester.

11. A method of making a composition of claim 1 , the method comprising:

adding N-acetylneuraminic acid and N-acetylneuraminic acid methyl ester to a composition comprising an antibiotic, wherein the concentration of the N-acetylneuraminic acid in the composition is between about 0.1 mg/mL to about 20 mg/mL and the concentration of the N-acetylneuraminic acid methyl ester in the composition is between about 0.1 mg/mL to about 20 mg/mL, and wherein the concentration of Tamiflu in the composition is about ¼ to about ¾ of the manufacturer's recommended dose for the treatment of influenza, or the concentration of the Enrofloxacin in the composition is about ¼ to about ¾ of the manufacturer's recommended dose for the treatment of rotavirus infection or diarrhea, or the concentration of the Tilmicosin in the composition is about ¼ to about ¾ of the manufacturer's recommended dose for the treatment of respiratory infections, respiratory syndrome, asthma, or other respiratory disorders, or the concentration of the Cephradine in the composition is about ¼ to about ¾ of the manufacturer's recommended dose for the treatment of diarrhea, dehydration, or gastroenteritis, or the concentration of the Tulathromycin in the composition is about ¼ to about ¾ of the manufacturer's recommended dose for the treatment of respiratory infections or disorders,

wherein the composition is a nutritional supplement, or a food, or a feed, or a medicated food additive, or a medicated feed additive, or a therapeutic composition, or a rehydration salt or a rehydration solution.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 18, 2018
From: WANG, HUIRU
To: B&H BIOTECHNOLOGIES, LLC
Reel/Frame 047807/0570 →
Continuity (2)
Provisional Application 61792984 · Mar 15, 2013
Related Publication 20160022713A1 · Jan 28, 2016