Tonsillectomy sponge
Described are methods of performing a surgical tonsillectomy, medical devices for treating a void created by removing tonsil tissue from a patient, surgical kits, and use of an extracellular matrix material in the manufacture of a medicament for treating a surgical wound resulting from removal of tonsil tissue from a patient. Also described is a device for wound closure, and methods of making and using thereof.
1. A surgical tonsillectomy method, comprising:
removing tonsil tissue from a patient, so as to create a surgical void;
implanting a wound closure device in the surgical void, the wound closure device comprising a remodelable sheet having a first edge and a second edge and a first surface between the first edge and the second edge and a second surface opposing the first surface, wherein the sheet is configurable from an open condition wherein the first edge and the second edge are spaced apart to a closed condition wherein the first edge and the second edge are brought together;
implanting a remodelable extracellular matrix foam material in the surgical void, said foam material effective to become infiltrated by native tissue; and
manipulating the remodelable sheet from said open position to said closed position to close the surgical void.
2. The method of claim 1 , wherein said extracellular matrix foam material comprises a dried remodelable extracellular matrix foam material.
3. The method of claim 2 , wherein said dried remodelable extracellular matrix foam material is compressed such that said foam material expands when wetted.
4. The method of claim 1 , further comprising closing the surgical void over the implanted foam material.
5. The method of claim 1 , wherein the remodelable extracellular matrix foam material retains at least one native growth factor from a source tissue.
6. The method of claim 1 , wherein the remodelable extracellular matrix foam material comprises one or more of submucosal tissue, renal capsule membrane, dermal collagen, dura mater, pericardium, amnion, fascia lata, serosa, peritoneum or basement membrane.
7. The method of claim 1 , wherein the remodelable extracellular matrix foam material further comprises a non-native bioactive component.
8. The method of claim 1 , further comprising partially closing the void so as to create a pocket, and wherein said implanting comprises delivering the foam material within said pocket.
9. The method of claim 8 , further comprising closing the surgical void over the implanted foam material.
10. The method of claim 1 , wherein the sheet is implanted into the surgical void and the extracellular matrix foam material is implanted onto the sheet.
11. The method of claim 10 , wherein the sheet and the extracellular matrix foam material are sized and configured such that the sheet envelopes the extracellular matrix foam material when the sheet is in the closed condition.
12. The method of claim 1 , further comprising a bioadhesive on the second surface of the sheet configured to adhere to patient tissue.
13. The method of claim 1 , further comprising a bioadhesive on the first surface of the sheet configured to secure the sheet in said closed position.
14. The method of claim 1 , wherein the remodelable sheet comprises an extracellular matrix material.
15. The method of claim 14 , wherein the extracellular matrix material retains one or more bioactive agents native to a source tissue for the extracellular matrix material.
16. The method of claim 14 , wherein said extracellular matrix material comprises one or more of submucosal tissue, renal capsule membrane, dermal collagen, dura mater, pericardium, amnion, fascia lata, serosa, peritoneum or basement membrane.
17. The method of claim 1 , wherein said manipulating causes said remodelable sheet to envelope said extracellular matrix foam material.
18. The method of claim 1 , the remodelable sheet having a plurality of perforations extending through the sheet from the first side to the second side.