Oral care compositions
View Patent ↗The present invention relates to oral compositions, comprising select phospholipid surfactants. Methods for using the compositions are also disclosed.
1. An oral composition, comprising:
i. a phospholipid surfactant selected from the group consisting of cocamidopropyl PG-dimonium chloride phosphate, myristamidopropyl PG-dimonium chloride phosphate, and mixtures thereof, wherein the phospholipid surfactant is present in an amount of from about 0.01% to about 10% w/w of the total composition;
ii. one or more water-insoluble noncationic bioactive agents selected from the group consisting of thymol, eucalyptol, menthol, methyl salicylate and mixtures thereof in a total amount of from about 0.16% to about 0.28% w/v of the total composition; and
iii. at least one orally acceptable solvent comprising water.
2. The compositions according to claim 1 wherein one or more water-insoluble noncationic bioactive agents is a mixture of thymol, eucalyptol, menthol and methyl salicylate.
3. The composition of claim 2 wherein the phospholipid surfactant comprises myristamidopropyl PG-dimonium chloride phosphate.
4. The composition of claim 2 wherein the phospholipid surfactant comprises cocamidopropyl PG-dimonium chloride phosphate.
5. The compositions according to claim 1 further comprising an additional surfactant.
6. The compositions according to claim 5 wherein the additional surfactant is a nonionic surfactant.
7. The compositions according to claim 6 wherein the nonionic surfactant is a poly(oxyethylene)-poly(oxypropylene) block copolymer surfactant.
8. The composition according to claim 1 wherein the composition is essentially free of C 2 -C 4 monohydric alcohols.
9. The composition according to claim 8 wherein the composition is free of C 2 -C 4 monohydric alcohols.
10. The composition of claim 1 wherein the phospholipid surfactant comprises cocamidopropyl PG-dimonium chloride phosphate.
11. A method of treating plaque, gingivitis or gum disease, comprising the step of applying to the tissues of the oral cavity of a mammal in need of such treatment an amount of the composition of claim 1 effective to reduce symptoms associated with plaque, gingivitis or gum disease.
12. A method of treating or reducing symptoms associated with inflamed tissue, comprising the step of applying to the tissues of a mammal in need of such treatment an amount of the composition of claim 1 effective to reduce symptoms associated inflammation.
13. The composition of claim 1 wherein the phospholipid surfactant comprises myristamidopropyl PG-dimonium chloride phosphate.