Antimicrobial composition
View Patent ↗An antiseptic composition suitable for use on skin and wounds comprising a source of an antimicrobial agent and an agent which disrupts biofilms. More, particularly the invention relates to a composition capable of providing effective antimicrobial activity while at the same time avoiding wound and skin irritation and retardation of wound healing.
1. An antiseptic composition suitable for use on skin and wounds comprising a source of an antimicrobial agent that is silver, a buffering agent, wherein the pH is maintained at a pH of between 4 and 6, and EDTA or its salts as an agent which disrupts biofilms.
2. The antiseptic composition as claimed in claim 1 wherein the EDTA is in the form of the di-, tri- or tetra-basic salts of EDTA.
3. The antiseptic composition as claimed in claim 1 wherein the composition has a pH of between 4.5 and 5.5.
4. The antiseptic composition as claimed in claim 1 wherein the composition is in the form of a gel.
5. The antiseptic composition as claimed in claim 1 wherein the antimicrobial agent is ionic silver.
6. The antiseptic composition as claimed in claim 5 wherein the composition comprises from about 0.1% to about 10% by weight of ionic silver.
7. The antiseptic composition as claimed in claim 6 wherein the composition comprises from about 0.5% to about 1.5% by weight of ionic silver.
8. A method of making an antiseptic composition as claimed in claim 2 comprising the steps of adding EDTA as a tetrasodium salt in aqueous solution to an antiseptic composition comprising a source of an antimicrobial agent that is silver and then adjusting the pH of the composition to a pH of between 4 and 6.
9. A method of treating chronic wounds or burns comprising applying to a chronic wound or a burn the composition of claim 1 .