IP Library Granted Patent US 9,789,304
Granted Patent B2
US 9,789,304 · App. 14/805,355 · Granted Oct 17, 2017

Methods and systems for treating hypertension using an implantable electroacupuncture device

Inventors: Jeffrey H. Greiner (Valencia, CA); David K. L. Peterson (Valencia, CA); Chuladatta Thenuwara (Valencia, CA)
Assignee: Valencia Technologies Corporation
A61N1/0504A61H39/002A61N1/36117A61N1/36175A61N1/3756A61N1/37205A61H2201/5005A61H2201/5035A61H2201/5038A61H2201/5097A61N1/3605A61N1/36125A61N1/3758A61N1/3782Y10S128/907
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Quick Facts
Patent No.
US 9,789,304
App. No.
14/805,355
Granted
Oct 17, 2017
Kind
B2
Abstract

A method of treating hypertension in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to a target tissue location within the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein the duty cycle is a ratio of T 3 to T 4 , each stimulation session included in the stimulation sessions has a duration of T 3 minutes and occurs at a rate of once every T 4 minutes, and the electroacupuncture device comprises a central electrode of a first polarity and an annular electrode of a second polarity and that is spaced apart from the central electrode; and 2) applying, by the electroacupuncture device, the stimulation sessions to the target tissue location by way of the central electrode and the annular electrode in accordance with the duty cycle.

Claims (21)

1. A method of treating hypertension in a patient, comprising:

generating, by an electroacupuncture device implanted beneath a skin surface of the patient at an acupoint corresponding to a target tissue location within the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein

the acupoint comprises at least one of PC5, PC6, ST36, and ST37,

each stimulation session included in the plurality of stimulation sessions comprises a series of stimulation pulses,

the duty cycle is a ratio of T 3 to T 4 ,

each stimulation session included in the stimulation sessions has a duration of T 3 minutes and occurs at a rate of once every T 4 minutes, and

the electroacupuncture device comprises a central electrode of a first polarity centrally located and substantially planar on a first surface of a housing of the electroacupuncture device and an annular electrode of a second polarity and that is spaced apart from the central electrode; and

applying, by the electroacupuncture device, the stimulation sessions to the target tissue location by way of the central electrode and the annular electrode in accordance with the duty cycle.

2. The method of claim 1 , wherein the target tissue location is a median nerve of the patient.

3. The method of claim 1 , wherein the stimulation sessions are configured to reduce sympathetic activity within the patient.

4. The method of claim 1 , wherein T 3 is at least 10 minutes and less than 60 minutes, and wherein T 4 is at least 1440 minutes.

5. The method of claim 1 , further comprising receiving, by the electroacupuncture device from a device external to the electroacupuncture device, a control command that configures the electroacupuncture device for treating hypertension.

6. The method of claim 5 , wherein the receiving of the control command comprises detecting, with a magnetic sensor included in the electroacupuncture device, a magnetic field generated by the device external to the electroacupuncture device.

7. The method of claim 1 , wherein the housing is coin-sized and coin-shaped.

8. The method of claim 1 , wherein the annular electrode is located on the first surface of the housing.

9. The method of claim 1 , wherein the annular electrode comprises a ring electrode located around a perimeter edge of the housing.

10. The method of claim 1 , wherein the applying of the stimulation sessions to the target tissue location further comprises applying the stimulation sessions by way an electrode included on a lead connected to the electroacupuncture device.

11. The method of claim 1 , further comprising powering electronic circuits within the electroacupuncture device with a battery having an internal impedance of at least 5 ohms.

12. The method of claim 1 , wherein the annular electrode surrounds the central electrode and is spaced at least 5 mm from a center of the central electrode.

13. The method of claim 11 , wherein the battery is non-rechargeable.

14. The method of claim 13 , wherein the battery has a capacity less than 60 mAh.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded May 6, 2026
From: MEDTRONIC, INC.
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 075721/0223 →
SECURITY INTEREST Recorded Oct 27, 2023
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 065382/0738 →
SECURITY INTEREST Recorded Aug 4, 2021
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 057088/0352 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2020
From: VALENCIA TECHNOLOGIES CORPORATION
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 053684/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2015
From: GREINER, JEFFREY H.; PETERSON, DAVID K. L.; THENUWARA, CHULADATTA
To: VALENCIA TECHNOLOGIES CORPORATION
Reel/Frame 036146/0989 →
Continuity (10)
Continuation 14446500 · Jul 30, 2014
Division 13598575 · Aug 29, 2012
Provisional Application 61575869 · Aug 30, 2011
Provisional Application 61606995 · Mar 6, 2012
Provisional Application 61609875 · Mar 12, 2012
Provisional Application 61672257 · Jul 16, 2012
Provisional Application 61672661 · Jul 17, 2012
Provisional Application 61674691 · Jul 23, 2012
Provisional Application 61676275 · Jul 26, 2012
Related Publication 20150321007A1 · Nov 12, 2015