Augmented delivery catheter and method
View Patent ↗The present invention relates to a catheter apparatus with an anchoring device to stabilize the catheter tip when in use, such as when infusing, injecting, or delivering substances, devices or other catheters into a patient. The apparatus according to various embodiments deploys an anchoring device that stabilizes the catheter tip and enables adjustment of the blood flow during use.
1. A catheter apparatus for placement within a blood vessel to at least partially occlude the blood vessel, the catheter apparatus comprising:
an outer sheath having a distal end;
an inner sheath having a distal end, the inner sheath being axially translatable and fitting within the outer sheath; and
an expansile anchor mechanism deployable between collapsed and expanded configurations by axially translating the inner and other sheaths relative to one another,
wherein the expansile anchor mechanism comprises a distal end coupled to the distal end of the outer sheath and a proximal end coupled to the distal end of the inner sheath,
wherein the expansile anchor mechanism comprises a fluid permeable tubular mesh braid and an impermeable elastomeric membrane covering at least a portion of the tubular mesh braid to at least partially obstruct blood flow in the blood vessel when the expansile anchor mechanism is in the expanded configuration within the blood vessel, and
wherein the impermeable elastomeric membrane allows antegrade blood flow beyond a distal tip of the distal end of the outer sheath while limiting the blood flow to cause pressure in the blood vessel distal to the distal tip to be less than pressure in the blood vessel proximal to the distal tip when the expansile anchor mechanism is in the expanded configuration within the blood vessel.
2. The catheter apparatus of claim 1 , wherein the fluid permeable tubular mesh braid and the impermeable elastomeric membrane form at least one permeable portion and at least one impermeable portion of the expansile anchor mechanism.
3. The catheter apparatus of claim 2 , wherein the at least one permeable portion comprises a distal permeable portion adjacent the distal end of the expansile anchor mechanism and the distal end of the outer sheath, wherein the at least one permeable portion further comprises a proximal permeable portion adjacent the proximal end of the expansile anchor mechanism and the distal end of the inner sheath, and wherein at least one impermeable portion is positioned between the distal and proximal permeable portions.
4. The catheter apparatus of claim 2 , wherein the at least one impermeable portion is configured to contact an inner wall of the blood vessel when the expansile anchor mechanism is in the expanded configuration within the blood vessel.
5. The catheter apparatus of claim 2 , wherein the at least one permeable portion and the at least one impermeable portion allows blood flow or reflux within the blood vessel to be regulated or throttled by translating the outer and inner sheaths relative to one another to deploy the expansile anchor mechanism between the collapsed and expanded configurations.
6. The catheter apparatus of claim 2 , wherein the at least one permeable portion of the expansile anchor membrane is open to blood flow or reflux therethrough.
7. The catheter apparatus of claim 2 , wherein the at least one impermeable portion of the expansile anchor membrane is entirely impermeable to blood flow or reflux therethrough.
8. The catheter apparatus of claim 1 , wherein the expansile anchor mechanism is configured to exert a controlled axially force against an inner wall of the blood vessel when expanded to the expanded configuration therein.
9. The catheter apparatus of claim 1 , wherein the fluid permeable tubular mesh braid comprises a plurality of filaments defining a plurality of interstices between the filaments, and wherein at least a portion of the impermeable elastomeric membrane comprises one or more flaps at the interstices.
10. The catheter apparatus of claim 1 , wherein the fluid permeable tubular mesh braid comprises a plurality of filaments defining a plurality of interstices between the filaments, and wherein at least a portion of the impermeable elastomeric membrane is removed at one or more of the interstices.
11. A method of occluding a target site in a blood vessel, the method comprising:
advancing a catheter apparatus to the target site; and
expanding an expansile anchor mechanism of the catheter apparatus at the target site into an expanded configuration,
wherein expanding the expansile anchor mechanism comprises translating outer and inner sheaths of the catheter apparatus relative to one another to deploy the expansile anchor mechanism in the target site, the outer and inner sheaths of the catheter apparatus coupled to distal and proximal ends, respectively, of the expansile anchor mechanism,
wherein blood flow and/or reflux in the target site is occluded with the expansile anchor mechanism in the expanded configuration,
wherein the expansile anchor mechanism comprises a fluid permeable tubular mesh braid and an impermeable elastomeric membrane covering at least a portion of the tubular mesh braid to at least partially obstruct blood flow in the blood vessel, and
wherein the impermeable elastomeric membrane allows antegrade blood flow beyond a distal tip of the outer sheath while limiting the blood flow to cause pressure in the blood vessel distal to the distal tip to be less than pressure in the blood vessel proximal to the distal tip when the expansile anchor mechanism is in the expanded configuration within the blood vessel.
12. The method of claim 11 , wherein expanding the expansile anchor mechanism of the catheter apparatus comprises contacting the expanded expansile anchor mechanism against an inner wall of the blood vessel.
13. The method of claim 12 , wherein contacting the expanded expansile anchor mechanism against the inner wall of the blood vessel comprises contacting an impermeable portion of the expansile anchor mechanism with the inner wall of the blood vessel.
14. The method of claim 12 , wherein contacting the expanded expansile anchor mechanism against the inner wall of the blood vessel comprises exerting a controlled radial force against the inner wall with the expanded expansile anchor mechanism.
15. The method of claim 11 , further comprising regulating or throttling blood flow or reflux within the blood vessel by shifting the expansile anchor mechanism between the expanded configuration and a collapsed configuration.